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destroy completely; damage irreparably;
"You have ruined my car by pouring sugar in the tank!"
"The tears ruined her make-up"
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destroy or cause to fail;
"This behavior will ruin your chances of winning the election"
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reduce to bankruptcy;
"My daughter's fancy wedding is going to break me!"
"The slump in the financial markets smashed him"
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reduce to ruins;
"The country lay ruined after the war"
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deprive of virginity;
"This dirty old man deflowered several young girls in the village"
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fall into ruin