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- KLF6 gene suppresses hepatocellular carcinoma cell proliferation,which may be partially associated with the upregulation of p21(WAF1) expression. KLF6基因表达水平的下降可能在原发性肝癌发病机制中起到一定作用。 上调p21WAF1表达是KLF6基因抑制肝癌细胞增殖的重要途径.
- Aims: To investigate the killing effects of PNP/fludarabine suicide gene system on human hepatocellular carcinoma cell line BEL7402 in vitro. 目的:研究PNP/fludarabine自杀基因系统对人肝癌细胞系BEL7402的体外杀伤效应。
- Objective To evaluate the effect of selenomethionine (SeMet) on the apoptosis of hepatocellular Carcinoma cell line SMMC7402 and explore its mechanism. 摘要目的:研究硒蛋氨酸对肝癌细胞株SMMC7402生长的影响及其作用机制。
- AIM: To explore of the role of JNK/SAPK signal transduction system in the apoptosis of human hepatocellular carcinoma cell line HepG2 induced by arsenic trioxide (As2O3). 目的:探讨JNK/SAPK信号转导系统在三氧化二砷(As2O3)诱导人肝癌细胞株HepG2凋亡过程中的作用.
- AIM: To study the anti cancer activity of high grade unsaturated fatty acids from Isatis tinctoria L on BEL 7402 human hepatocellular carcinoma cell in vitro . 目的 :研究板蓝根高级不饱和脂肪组酸体外抗人肝癌BEL 74 0 2细胞的活性。
- Key words: Vitamin K2;invasion;metastasis;hepatocellular carcinoma cells. 关键词:维生素K2;肝癌;侵袭;转移;生长抑制。
- Objective To comparatively study the apoptosis-inducing effects of chemotherapy and thermochemotherapy of ADM on human hepatocellular carcinoma cell line(BEL7402) and human multidrug-resistant hepatocellular carcinoma cell line(BEL7402/ADM). 目的探讨阿霉素(ADM)加热化疗对人肝癌细胞BEL7402(以下简称BEL7402细胞)及其耐药株BEL7402/ADM细胞(以下简称BEL7402/ADM细胞)的凋亡诱导作用。
- Objective To evaluate the cytotoxicity of hydroxyapatite (HAP) nanoparticles on human hepatocellular carcinoma cell line BEL 7402 by means of growth inhibition and apoptosis induction in vitro. 目的 从抑制细胞生长增殖和诱导细胞凋亡角度评价羟基磷灰石纳米粒子对人肝癌BEL 740 2细胞的细胞毒性。
- Objective To investigate the suppression of MDR1 and P-glycoprotein induced by small interfering RNA and the restoration of sensitivity to chemotherapeutic drugs in multidrug-resistant hepatocellular carcinoma cell line Bel7402/5-Fu. 目的:研究小片段RNA干扰对肝癌耐药细胞系Bel7402/5-Fu中多药耐药基因(multidrugresistance1,MDR1)及其蛋白产物P-gp表达的抑制作用和逆转其耐药性的效果。
- Objective To observe the toxicity, apoptosis and cell proliferation cycle of Mangiferin on the BEL 7404 human hepatocellular carcinoma cell line, and explore the possibility of Mangiferin as a new tumor chemopreventive drug. 目的 观察芒果甙对人肝癌细胞株BEL 74 0 4的毒性和诱导凋亡作用及对细胞周期的阻滞作用 ,探讨芒果甙作为肿瘤化学预防药物的可能性。
- Methods The hepatocellular carcinoma cell lines HCC 9903, EGHC 9901,HCC 9901 and HCC 9810 were respectively detected by fluorescence in situ hybridization (FISH) centromere DNA probes of X chromosome. 方法 制备三株新建人肝细胞肝癌细胞系 HCC- 990 3、EGHC- 990 1、HCC- 9810染色体标本 ,用 X染色体着丝粒特异 DNA探针 ,对其 X染色体进行荧光原位杂交 (FISH) ,检测 X染色体拷贝数畸变。
- Objective: To study sodium cantharidate induced apoptosis of human hepatocellular carcinoma cells in vitro. 目的:探讨斑蝥酸钠体外诱导肝癌细胞的凋亡。
- Objective: To investigate the mechanism of tumor escape through the Fas/FasL system in hepatocellular carcinoma cells (HCC). 目的 :研究肝癌细胞表面 Fas/ Fas L系统的变化及对其逃避机体免疫监控的影响。
- There was a good time and dose effect dependent manner and Bel 7402 hepatocellular carcinoma cells were inhibited by HAP nanopaticles. HAP纳米粒子在体外对人肝癌细胞系Bel 74 0 2具有明显的抑制作用 ,并呈现良好的量效和时效关系。
- Abstract: Object To study the inhibitory effects of vitamin K2 on invasion and metastasis ability of hepatocellular carcinoma cells. 摘要目的研究维生素K2对人肝癌细胞的体外抗黏附、抗侵袭转移及生长抑制作用。
- Conclusion Combined treatment of TACE and PEI can effectively eliminate circulating hepatocellular carcinoma cells and thereby prevent metastasis and recurrence of HCC. 结论联合TACE及PEI治疗复发性肝癌可有效地杀灭血液中播散的循环性肝癌细胞,可预防肝癌再复发和转移的发生。
- It was found that wild-type gene PTEN could suppress the proliferation of hepatocellular carcinoma cells and induce G1 phase block wile the mutated PTEN gene lost this function. 本课题最后发现野生型PTEN基因可抑制肝癌细胞的增殖,诱导G1期阻滞;而突变的PTEN基因无上述作用。
- Human hepatocellular carcinoma cell line QGY-7701 人肝癌细胞株QGY-7701
- hepatocellular carcinoma cell line (HCC-9724) HCC-9724细胞
- hepatocellular carcinoma cell line of mice( H22 ) 小鼠肝癌H22细胞