It was found that wild-type gene PTEN could suppress the proliferation of hepatocellular carcinoma cells and induce G1 phase block wile the mutated PTEN gene lost this function.

• 本课题最后发现野生型PTEN基因可抑制肝癌细胞的增殖，诱导G1期阻滞；而突变的PTEN基因无上述作用。