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- receptor down regulation 受体衰减性调节
- The blockade of AT 1 receptor may down regulate the excitability of adrenergic neurons in Arc, Pe and AHP induced by CBC. 阻断脑血管紧张素能AT1受体对胆碱能刺激引起Arc、Pe和AHP的儿茶酚胺能神经元兴奋性有下调作用。
- The mechanism is possibly that dysfunction of hMLH1 gene brig about the down regulation of PTEN gene expression. PTEN和hMLH1蛋白表达也会影响胃癌的部分生物学行为,其机制可能是hMLH1基因功能缺陷导致PTEN基因表达下调。
- Haque S,Haque A,Kasper LH.Toxoplasma gondii-derived factors stimulates immune down regulation:a vitro mode[J].Immmunology,1995,63(9):3442. 吴少亭;吕芳丽;石佑恩.;感染弓形虫小鼠早期细胞免疫的探讨
- Conclusion: Down regulation of CK19 gene was found in colorectal cancer and lung cancer, further study on role of CK19 in cancer progress is promising. 结论：在大肠癌、肺癌组织出现CK19的表达下调，与大肠癌、肺癌的发生发展的相关性值得进一步研究。
- These data further confirm that the anti-proliferative effect of ATRA on OPM-2 cells is caused both by the down regulation of IL-6R and the inhibition of IL-6 production. 这进一步证明ATRA对OPM-2细胞增殖的抑制作用是通过下调IL-6R及抑制瘤细胞自分泌IL-6双重作用而实现的。
- These results suggest that the down regulation of cyclin D1, CDK4 and pRb proteins may be related to the effects of cholesterol deficiency on proliferation of Jurkat cells. 结果提示，无论是内源性还是外源性胆固醇的缺乏都能抑制Jurkat细胞的增殖，推测这种变化可能与cyclin D1、CDK4及pRb 蛋白表达量的下降而导致相应的cyclin D1/CDK4复合活性下降有关
- Disoprofol can protect the brain and its mechanism might be relate d to the down regulation of three apoptosis associated genes including APAF1,DEF T and STM- 2. 异丙酚具有脑保护作用,其机制可能与APAF1,DEFT和STM-2三个凋亡相关基因下调
- Down regulation of insulin receptors and the change of TPK activity might be a key factor in the mechanism by which the MODS patients developed insulin resistance. 胰岛素受体酪氨酸激酶活性改变可能是MODS患者胰岛素抵抗发生的分子基础。
- CONCLUSION: Down regulation of MAD2 expression of SGC7901 bv sequence-specific siRNA could accelerate the cell growth and impair the mitosis arrest of SGC7901 induced by VCR. MAD2的抑制可使胃癌细胞SGC7901生长加速,增殖能力增强,同时减弱纺锤体抑制剂长春新碱阻滞细胞周期的作用。
- The prevention of the down regulation of GJIC by the tumor promoters or the restoration of GJIC in neoplastic cells may have potential in prevention and therapy of cancer. 阻止肿瘤促进剂对细胞GJIC功能的抑制或恢复癌细胞GJIC功能将对肿瘤的预防和治疗具有重要意义。
- Have a glass of beer to rinse your dinner down. 喝杯啤酒把你吃的晚饭冲下去。
- The machine must break down at this busy hour. 正忙的时候，机器偏偏又坏了。
- The old man stared the uninvited guest up and down. 老人把不速之客上下打量了一番。
- Down regulation of E CD expression correlates with bad biological behavior and poor prognosis of gastric cancer. The reduction of E CD expression may take place during early time of gastric cancer. 胃癌组织E－CD表达下调与胃癌较恶的生物学行为及预后不佳密切相关，并发生于胃癌的早期阶段。
- Expression of p-selectin in renal tissue was down regulated after using of either urokinase or papaverine. 5. 4.;通过免疫组织化学染色，观察到了罂粟碱或尿激酶应用后，缺血再灌注损伤大鼠肾脏组织内p-selectin表达的下调。
- He let himself down slowly by means of a tope. 他借助一根绳子慢慢地下来了。
- The deer was peppered with shot all down one side. 那只死鹿的半边身子都被子弹击中。
- The L type calcium channel and SR Ca 2+ ATPase were down regulated in DHF. These changes may be a contributory factor for DHF. 细胞膜L型Ca2 + 通道和SR钙泵mRNA和蛋白质表达减低是导致心肌细胞内Ca2 + 超负荷及DHF发生的?
- The maid did down the walls with a duster. 女佣用掸帚由上而下地刷除四壁上的尘垢。
