These data further confirm that the anti-proliferative effect of ATRA on OPM-2 cells is caused both by the down regulation of IL-6R and the inhibition of IL-6 production.

• 这进一步证明ATRA对OPM-2细胞增殖的抑制作用是通过下调IL-6R及抑制瘤细胞自分泌IL-6双重作用而实现的。