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- Pharmaco-pathology is a novel branch in clinical pathology, whose main work is identifying molecular targets on tumor tissues by pathological methods and supplying evidence for targeted drug therapy. 药物病理学是临床病理学领域的新兴分支学科,其主要工作是利用病理学手段识别肿瘤组织存在的分子靶点,为临床针对性靶向治疗提供用药依据。
- The efficacy of CDA-II is based on its molecular targeting ability.Molecular targeting drugs that target tumor genes are the highlight of the new anti-cancer drugs development. CDA-II的有效性也建立在它对分子靶点的选择性,癌基因分子靶点药物是目前开发抗癌新药的热门。
- Survival of advanced CRCs has achieved more than 24 months with the use of new chemotherapeutic agents, especially when combining with molecular targeted drugs. 与此同时,新的治疗方法和药物也在不断问世,分子靶向药物是发展最快的一个方向,特别是单克隆抗体与传统的化疗药物的联合已经使得晚期大肠癌患者的生存期超过了24个月。
- molecular target drug 分子靶向药物
- Keywords molecular targeted drug gefitinib treatment;research progress; 分子靶向药物吉非替尼;治疗;研究进展;
- So MAPK can serves as a molecular target for diseases treatment. 因此,MAPK是潜在的治疗分子靶。
- The relationship between pharmacogenetics and drug therapy(including treatment outcome and toxicity),and molecular target therapy of cancer are discussed in this review. 该文主要对药物遗传学与肿瘤药物治疗(包括药物治疗结果与毒副反应)、分子靶向治疗的关系进行综述。
- It is a potential molecular target for tumor-selective drug delivery,including delivery of radiolabeled folate-chelate conjugates for diagnostic imaging. 在肿瘤靶向药物输运体系中,包括输运放射性核素标记的叶酸螯合物显像剂,叶酸受体是一种潜在的分子靶。
- Molecular Targeting Drug 分子靶向药物
- The recent discovery of several genes whose malfunctioning leads to Alzheimer's provides the pharmaceutical industry with important molecular targets for drug development. 最近发现的几种导致早老性痴呆症的有缺陷基因给制药业提供了重要信息以找出针对这些细胞靶的有效药物。
- Monoclonal antibody (McAb) was highly specific to its antigen and could be made for specific molecular target sites. 苯并二吡咯类抗生素有极强的细胞毒性,抗肿瘤活性强;
- For each molecular target, such as cocaine, a corresponding aptamer can be selected from a large DNA library. 对于一个分子靶标(如可卡因)来说,可以从DNA库中选出相对应的核酸适体。
- "The field is awash with different results in various cells, but no real identification of a specific molecular target for these substances. “这个领域被多种细胞的不同结果刷新,但这些物质中没有一个真正的特异性分子靶点被鉴定。
- Study the anti-cancer molecular mechanism of Ping Xiao Jiao Capsule,and discovery the molecular target through experimental obversation inVitro . 2、通过体外实验观察,研究平消胶囊治疗乳腺癌的抑瘤分子机制,发现其在分子水平的作用靶点。
- Its molecular target was identified as human methionine aminopeptidase 2 (huMetAP 2),resulting in specific inhibiting growth and proliferation of vascular endothelial cell. 该类药物通过共价抑制甲硫氨酰氨肽酶2的活性,而特异性地抑制血管内皮细胞的生长和增殖。
- Major Interests : Novel techniques in molecular diagnostics in genetics diseases, cancer, and serious infectious diseases.Also include nanomaterials in immunoassays and targeting drug delivery. 研究兴趣 :分子诊断(遗传病,肿瘤,重大传染病等),生物纳米材料在免疫诊断及药物靶向输送的应用。
- Molecular targeted drugs 分子靶向药物
- AIM To develop an orally administered colon targeting drug delivery system dexamethasone succinate dextran (DSD) tablets. 目的研制口服结肠定位释放药物的地塞米松葡聚糖酯及其片剂。
- The concentration of DSP was measured by HPLC, and used to calculate the relative targeting drug delivery index(DDI) of DSP. 分别给大鼠口服各种DSP制剂,测定经时血药浓度和结肠组织中分布量,计算药物的相对靶向释药指数(DDI)。
- Allelic loss at the FRA3B site occurs frequently in NPC. This suggests that the region between D3S4103 and D3S4260 may represent a preferential molecular target in nasopharyngeal carcinogenesis. FRA3B脆性部位的LOH为鼻咽癌的频发事件,可能参与了鼻咽癌的发生发展,共同缺失区D3S4103-D3S4260可能是其优先作用的分子靶点。