Its molecular target was identified as human methionine aminopeptidase 2 (huMetAP 2),resulting in specific inhibiting growth and proliferation of vascular endothelial cell.

• 该类药物通过共价抑制甲硫氨酰氨肽酶2的活性,而特异性地抑制血管内皮细胞的生长和增殖。