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- STT exerts its cytotoxic effect on BEL-7402 cells by inducing apoptosis. STT在体外能抑制BEL 74 0 2细胞的增殖并能诱导细胞凋亡 ,其诱导凋亡作用的途径之一是下调Bcl 2蛋白表达。
- HSV - tk/ACV system showed strong cytotoxic effect, which suggested to has a strong bystander effect in vivo. 在体内HSV-tk/ACV系统具有强的细胞毒作用,提示存在着强的旁观者效应。
- OBJECTIVE:To study the cytotoxic effect in vitro and antitumor effect in vivo of hypericum chinense. 目的:研究金丝桃体外细胞毒作用和体内抗肿瘤作用。
- Objective To study the relationship between recurrent spontaneous abortion and the cytotoxic effect of NK cells. 目的探讨复发性自然流产(RSA)的发生与自然杀伤(NK)细胞杀伤活性的关系。
- Liquid cell culture and conventional chromosome assay were used to evaluate the cytotoxic effect of IFN,HHT and Ara c on CML Ph + cell. 以药物作用 2 4小时液体培养及常规染色体分析法研究 IFN、HHT及 Ara- c对 10例 CML 慢性期患者的骨髓中 Ph+ 细胞的生长影响。
- Abstract Objective To study the cytotoxic effect of thiotepa (THT) and mitomycin C (MMC) on human bladder cancer cell line in vitro. 摘要 目的 探讨体外膀胱灌注噻替哌和丝裂霉素C药物浓度和作用时间对膀胱癌细胞杀伤作用的影响。
- Thus, a hypercalcemia-induced cytotoxic effect in the central nervous system may play an important role in neuropsychiatric manifestations. 许多证据显示高血钙可于中枢神经系统造成细胞的毒性效应，而扮演导致神经精神症状之重要角色。
- Objective To prepare a bispecific antibody (BsAb) against CD3 and TNP and to test its cytotoxic effect against the gastric cancer cell line,MGC803. 目的以化学方法将抗CD3及抗三硝基苯(TNP)单克隆抗体交联为双功能抗体,研究此双功能抗体与任何TNP化的抗肿瘤单抗结合,介导对肿瘤细胞的杀伤作用。
- We found that ten or more essential oils showed a significant cytotoxic effect on human nasopharyngeal carcinoma (CNE cell line). 结果:发现10多种精油对入鼻咽癌(CNE细胞株)有很强的细胞毒性。
- The dynamic relationship between cytotoxic effect and incubated time with TPT was investigated by flow cytometry and immunological analysis. 应用新的流体细胞测量仪(FACS-Vantage)及免疫分析法对细胞培养时间、TPT的浓度与拓扑酶中毒程度的动力学关系进行了研究。
- The pathogenic process of pneumonia infected by Streptococcus pneumoniae includes adherence, inflammatory reaction, and cytotoxic effect of virulent factors. 肺炎链球菌致病过程包括粘附,炎症反应,细菌产物的细胞毒作用。
- Another limitation in the choice of targets and antibodies arises with immunotoxins, which require internalization in order to hae a cytotoxic effect on tumour cells. 由于需要细胞内化的过程以使肿瘤细胞内部产生细胞毒效应，免疫毒素还面临在治疗对象和单抗选择方面的局限。
- Pang JX,Ma RQ,Liu LM,et al.Total alkaloid of Macleaya cordata:in vitro cytotoxic effect on Hep3B cells and in vivo antitumor effect in mice[J].J South Med Univ,2005,25(3):325-8. [5]庞建新;马仁强;刘兰梅;等.;博落回总碱对肝癌细胞的毒性作用和体内抗肿瘤作用[J]
- Conclusion Ethanol extract of eupolyphaga have cytotoxic effect in vitro, nor do water extract.It is valuable to investigate the mechanism of cytotoxic effect. 结论 体外土鳖虫水提物没有抗肿瘤活性，醇提物有较强的抗肿瘤作用，值得进一步研究其抑制机理。
- Cytotoxic effect of PQ on PC12 cellsCytotoxic effects of PQ on PC12 cells were investigated in this study. 百草枯对PC12细胞的损伤作用
- The cytotoxic effects of CDDP plus 20ug/ml, 13ug/ml CA were statistically significantly more cytotoxic than Cdd? 结果提示,20 ug/ml与13 ug/ml CA对CDDP有增敏作用。
- Its cytotoxic effects and dosage-dependent relationship on growth of tumor cells were examined by MTT assay. 用溴化二苯四偶氮盐比色法检测其对体外培养的人癌细胞的细胞毒作用,探索量效关系。
- CIK cells can down regulate the expression of P glycoprotein in MCF7 adr cell line remarkably, and synergistic cytotoxic effect against MCF7 adr cell line can be detected when combined with ADR. CIK细胞可明显抑制MCF7adr肿瘤细胞系的P gp表达 ,可协同阿霉素提高对MCF7adr肿瘤细胞系的杀伤活性。
- Objective To observe pathomorphological changes of nonpigmented epithelial cells (NECs) of ciliary body after local single application of mitomycin C (MMC) during sclerectomy in rabbit eyes, and to explore cytotoxic effect of MMC on ciliary body. 目的观察兔眼巩膜咬切术中应用0.;2mg/ml丝裂霉素C（MitomycinC，MMC）后，睫状体无色素上皮细胞的病理形态学的改变，探讨MMC对睫状体的毒性作用。
- Results of the MTT assay showed that GBS exhibits a significant cytotoxic effect in HL-60 cells, and we found that the cytotoxic effect is a result of apoptosis as evidenced by morphological change, DNA fragmentation, and flow cytometry. MTT还原测定(单核细胞直接细胞毒性测定)结果显示GBS对HL-60细胞有明显的细胞毒作用,通过形态学改变、DNA断裂及流式细胞计量术,我们发现其细胞毒作用是凋亡的结果。
