Objective To prepare a bispecific antibody (BsAb) against CD3 and TNP and to test its cytotoxic effect against the gastric cancer cell line,MGC803.

• 目的以化学方法将抗CD3及抗三硝基苯(TNP)单克隆抗体交联为双功能抗体,研究此双功能抗体与任何TNP化的抗肿瘤单抗结合,介导对肿瘤细胞的杀伤作用。