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- bispecific antibody molecule 双特异性抗体分子
- Scientists call this claw shape the antibody molecule's idiotype. 科学家称这种爪型为抗体微小颗粒的遗传型。
- The bispecific antibody could induce P BLs to cytotoxic test of colonic cells in vivo. 双功能抗体能够介导PBLs对CL187细胞的杀伤作用。
- The construction of a single-chain bispecific antibody COC183B2/anti-CD3 was successful. 成功构建抗人卵巢癌COC183B2 /抗CD3scBsAb ;
- Objective To prepare a bispecific antibody (BsAb) against CD3 and TNP and to test its cytotoxic effect against the gastric cancer cell line,MGC803. 目的以化学方法将抗CD3及抗三硝基苯(TNP)单克隆抗体交联为双功能抗体,研究此双功能抗体与任何TNP化的抗肿瘤单抗结合,介导对肿瘤细胞的杀伤作用。
- Conclusion: The second set hybridtumortechnology to prepare the bispecific antibody had a homogeneous titer, an idealsignal-to-noise ratio and was easy to be standardized. 结论:采用二次杂交瘤技术制备的双功能抗体优于化学偶联法,抗体效价具有均匀性和理想的信噪比,抗体易于标准化。
- A single-chain bispecific antibody COC183B2/anti-CD3 is constructed and expressed successfully, which can keep approximately the antigen-binding affinity of the two parent ScFvs. 构建和表达抗人卵巢癌COC183B2 /抗CD3scBsAb成功 ,且具有与抗原OC183B2、CD3结合的免疫学活性
- The number of components of an antigen molecule to which an antibody molecule can bind. 效价能和抗体分子结合的抗原分子的组成成分的数目
- These are the antibody molecules. 这些是抗体微小颗粒。
- In order to improve the therapeutic utility of antibodies, different modifications have been suggested.One of them concerns the generation of bispecific antibody (BsAb). 为了增强抗体的效应功能,人们尝试多种方法改造抗体分子,双特异性抗体是改善抗体治疗效果的发展方向之一,现已成为抗体工程研究领域的热点。
- Antibody molecules also serve as receptors on the surface of B cells. 同时,抗体分子在B细胞表面也可作为受体存在。
- Antibody molecules also sere as receptors on the surface of B cells. 同时,抗体分子在B细胞表面也可作为受体存在。
- Keywords Biological therapy;mRCA;CD55;Bispecific antibody; 免疫生物学治疗;膜补体调节蛋白;CD55;双特异性抗体;
- Keywords Bladder carcinoma;Bispecific antibody;LAK cells;Cytotoxicity; 膀胱癌;双功能抗体;LAK细胞;细胞毒性作用;
- The chemical blocker is known to readily dissociate the antibody molecules physically adsorbed(30). 大家都知道,化学封闭剂能将物理吸附的抗体游离。
- The chemical blocker is known to readily dissociate the antibody molecules physically adsorbed (30). 大家都知道,化学封闭剂能将物理吸附的抗体游离。
- Scientists have long known that, fundamentally, lupus arises from an immunological malfunction involving antibody molecules. 科学家很早就知道,狼疮是因为体内免疫系统的抗体分子失常所引起。
- The narrow opening of this canyon possibly prevents the relativly large antibody molecules from binding to the common sequence, but smaller molecules might reach it. 该“峡谷”狭窄的开口可能会阻止较大的抗体分子与普通序列的结合,但较小的分子或许能抵达普通序列。
- Advance in Manufacture Method of Bispecific Antibody and Application in Treat of Dairy Cow Mastitis 双特异性抗体的研制方法及其在奶牛乳腺炎治疗中的应用
- Construction and expression of a single-chain bispecific antibody COC183B2/anti-CD3 against human ovarian carcinoma 抗人卵巢癌COC183B2/抗CD3单链双特异抗体的构建和表达