Conclusion: The second set hybridtumortechnology to prepare the bispecific antibody had a homogeneous titer, an idealsignal-to-noise ratio and was easy to be standardized.

• 结论:采用二次杂交瘤技术制备的双功能抗体优于化学偶联法,抗体效价具有均匀性和理想的信噪比,抗体易于标准化。