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- Sotalol Hydrochlofide 盐酸索他洛尔
- Objective To synthesis Sotalol hydrochloride. 合成盐酸索他洛尔。
- Electrophysiological Studies of Origin for Early Afterdepolarization Induced by Sotalol in Vivo. 在体心脏早期后除极起源的电生理学研究。
- After intravenous administration of 0.5 mg/kg and 1.0 mg/kg sotalol,no EAD and TdP occurred. 静注索他洛尔 0 .;5mg kg和 1
- Objective To assess the clinical therapeutic effect of sotalol on atrial paroxysmal fibrillation. 目的研究索他洛尔对控制国人阵发性心房颤动的疗效、合适剂量和安全性。
- Abstract 0bjective：To establish bacteria endotoxin test for monitoring pyrogen in Sotalol Hydrochloride injection. 摘 要 目的：探讨盐酸索他洛尔注射液细菌内毒素检查法的可行性。
- Xiao-Dong Yu, Fan-Hong Wu, Shi-Hui Wu, the synthesis of anti-arrhythmic drug Sotalol, Chemical World, 39, 84 (1998). 吴范宏，黄维垣，含氟聚醚的合成研究：3-氧杂全氟戊烷-1,5-二磺酰溴和二烯的共聚反应，中日氟化工和精细化学品研讨会论文集，桂林，1998。
- Objective: To observe the efficacy of sotalol in the treatment of paroxysmal atrial fibrillation. 摘要目的：观察索他洛尔治疗阵发性心房颤动的疗效。
- Early afterdepolarizations (EADs) and APD alternant were induced by d - sotalol in M cells but they were not found in endocardinm and epicardium. d-索他洛尔作用于M细胞,诱发早期后除极(EADs)和APD交替变异,而心内膜、外膜细胞则未见。
- If these agents either prove ineffective or produce side effects, then amiodarone, dofetilide, and sotalol represent appropriate secondary choices. 如果这类药物无效或者出现不良反应，胺碘酮、多菲莱德和索他洛尔是合适的二线选择；
- Conclusion: The therapeutic effect of sotalol in the treatment of paroxysmal atrial fibrillation is better than propafenone. 结论：索他洛尔治疗阵发性心房颤动疗效优于普罗帕酮。
- Themost prominent effect of sotalol was the prolongation of action potential duration(APD)and effective refractory perid(ERP)of the SAN,AVN,atrial and His-bun-dle cells. 标本被驱动时,心房SAN 逆传时间与房-室传导时间均被 Sot 延长。
- The pharmacologic action and clinical investigation of new anti-atrial fibrillation drugs,such as dofetilide,sotalol,ibutilide are reviewed in this paper. 本文对多非利特、索他洛尔、伊布利特等新的治疗心房颤动的药物的药理作用、临床研究情况作一介绍。
- Results: The effective rates in sotalol group and propafenone group were 75% and 63%, respectively.There were significant differences between two groups (P<0.05). 结果：索他洛尔治疗组有效率75%25，普罗帕酮组有效率63%25，两者有显著差异(P<0.;05)。
- APD_(95) and ERP of PF and VM could be prolonged markedlyby sotalol Increase in APD_(95) after sotalol was significantly greater in NZ thanIZ fibers, whereas ERP was more prolonged in IZ than in NZ fibers. Sotalol显著延长NZ与IZ区VM及PF的动作电位时程(APD_(95))和有效不应期(ERP),并且延长ENDO的APD_(95)与ERP的程度超过EPI。
- levo- cetirizine hydrochlofide tablets 盐酸左西替利嗪片
- Methods In order to get Sotalol,benzenamine was acetylated by methylsulfonylchloride and bromoacetylbro mide b y turns,then substituted with isopropylamine by S N1 reaction and reduced in th e end. 方法以苯胺为原料,经甲烷磺酰氯的酰化反应,溴乙酰溴的傅-克酰化反应和异丙胺的分子间亲核取代反应及还原四步合成盐酸索他洛尔。
- Acetyl-L-camitine hydrochlofide tablet 盐酸乙酰左卡尼汀片
- Torsade de pointes induced by sotalol 索他洛尔致尖端扭转性室性心动过速一例
- Keywords Metformin hydrochlofide Preparation Drug release; 盐酸二甲双胍;制备;释放度;
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- 深远海浮式风电平台 - deep-sea floating wind power platform
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- 京雄高速公路 - Beijing-Xiongan expressway
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- 农业及相关产业增加值 - the added value of agriculture and related industries
