APD_(95) and ERP of PF and VM could be prolonged markedlyby sotalol Increase in APD_(95) after sotalol was significantly greater in NZ thanIZ fibers, whereas ERP was more prolonged in IZ than in NZ fibers.

• Sotalol显著延长NZ与IZ区VM及PF的动作电位时程(APD_(95))和有效不应期(ERP),并且延长ENDO的APD_(95)与ERP的程度超过EPI。