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- homoserine acetyltransferase 高丝氨酸乙酰基转移酶
- Homoserine has also been implicated in the biosynthesis of methionine. 同型丝氨酸也牵涉到蛋氨酸的生物合成。
- These help a mitochondrial enzyme called carnitine acetyltransferase to do its job. 这两种分子有助于被称作肉碱乙酰转移酶的线粒体酶发挥作用。
- However, classical research methods which merely focus on single protein are still utilized to study acetyltransferase and deacetylase of Homo sapiens. 目前对于乙酰化酶和去乙酰化酶的研究还基本上是传统的单个蛋白的研究方法。
- Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis. 原文:Liu D; Lepore BW; Petsko GA; Thomas PW; Stone EM; Fast W; Ringe D.
- A novel short-root gene encodes a glucosamine-6-phosphate acetyltransferase required for maintaining normal root cell shape in rice. 异常的短根基因编码维持水稻根细胞形态所必需的6-磷酸氨基葡萄糖乙酰基转移酶。
- Objective:To study the impacts of pathological pain on apoptosis of hippocampus and content of choline acetyltransferase(CHAT) in old male rats. 目的:研究病理性疼痛对老年雄性大鼠海马细胞凋亡和胆碱乙酰转移酶(CHAT)含量的影响。
- Title: Cloning, expression and transcriptional activity of Bm-mof, an MYST histone acetyltransferase gene in the silkworm, Bombyx mori L. 关键词:家蚕;MYST组蛋白乙酰转移酶;克隆;序列分析;表达谱
- This was further supported by the observation that the increasing effect of HS4 was counteracted by histone acetyltransferase inhibitors. 通过加入组蛋白乙酰基转移酶抑制剂,我们观察到HS4的增强作用受到了抑制,这使我们更加确信上述的观点。
- The three dimensional structure of homoserine transsuccinylase from Escherichia coli(EcHTS) was modeled by using homology and molecular dynamics methods. 利用同源模建和分子动力学模拟方法,模建了大肠杆菌中高丝氨酸琥珀酰基转移酶的三维结构。
- In addition, by using the HAT domain-deleted p300 mutant, weshowed that the histone acetyltransferase activity of p300/CBP was important in regulation ofWT1 gene expression. 此外,通过采用HAT区缺失突变的p300表达质粒的转染实验,我们证明了p300/CBP的组蛋白乙酰转移酶活性在WT1基因转录调控过程中发挥重要作用。
- High efficient expression of Pro-X lays the foundation for serum assay of PBC patient by prokaryotic expression of dihydrolipoamide acetyltransferase compounds . 获得Pro-X蛋白的原核高效表达,为利用原核表达的丙酮酸复合物对PBC患者进行血清学检测进一步奠定了基础。
- By designing four primers for an overlapping PCR, we created a fusion gene Ddl cat encoding human TNF receptor I death domain and chloramphenicol acetyltransferase(CAT). 通过设计4个引物进行重叠(overlapping)PCR,由此克隆了人肿瘤坏死因子受体I死亡域(deathdomain)与氯霉素乙酰转移酶(CAT)的融合蛋白基因(DdLcat)。
- Some Enterobacteriaceae produce an aminoglycoside acetyltransferase enzyme, AAC(6’)-I, that results in a gentamicin-S, tobramycin-R, and amikacin-R phenotype. 某些肠杆菌科菌产生氨基糖甙乙酰转移酶[AAC(6’)-I],可致庆大霉素-S、妥布霉素-R、阿米卡星-R的表型。
- A range of bacterial species use N-acyl homoserine lactone (AHL) molecules as quorum senging signal to regulate different biological functions, including production of virulence factors and bioflim formation of human pathogens. 细菌的群体感应系统(Quorum sensing,QS)参与许多生物学功能的调控,其中包括动植物病原细菌致病因子的生成以及人类某些病原细菌生物膜的形成。 酰基高丝氨酸内酯(N-acylhomoserine lactone,AHL)是调控群体感应系统的关键信号分子。
- Bacterial Quorum-sensing,in which N-acyl homoserine lactone (AHL) acts as a key singnal is involved in regulation of diverse biological function,including production of virulence factors and bioflim formation of human pathogens. 细菌的群体感应系统(Quorum sensing,QS)参与许多生物学功能的调控,其中包括动植物病原细菌致病因子的产生以及人类某些病原细菌生物膜的形成。 酰基高丝氨酸内酯(N-acylhomoserine lactone,AHL)是调控群体感应系统的关键信号分子。
- For example, histone acetyltransferase (HAT) complexes are thought to activate gene expression by modifying chromatin-associated proteins called histones which function like spools for DNA to wind around. 例如,组蛋白乙酰转移酶(HAT)复合物被认为是通过修饰与染色质相连的被称作组蛋白的蛋白质来激活基因表达的过程,而组蛋白的功能是被当作让DNA缠绕的线轴。
- Taken together, these results significantly advance the understanding of mechanisms that permit fine-tuning of transcriptional regulation by revealing that the hSAGA histone acetyltransferase complex is also capable of histone deubiquitylation. 综上所述,这些结果披露了hSAGA组蛋白乙酰转移酶复合物同时也具有将组蛋白去泛素化的能力,因而大大增进了人们对转录调节过程的精微调节机制的理解。
- In AD brain, the activity of choline acetyltransferase (acetyl CoA: choline O-acetyltransferase, EC 2.3.1.6, ChAT) and the level of neurotransmitter acetylcholine (ACh) obviously reduced. AD患者胆碱能神经细胞明显丢失;胆碱能神经纤维发生退变;导致中枢胆碱能系统功能紊乱;皮层、基底前脑的胆碱乙酰化转移酶(acetylCoA:choline-O-acetyltransferase;EC2.;3
- Recent studies showed that some transcriptional regulators with histone acetyltransferase(HAT) and deacetylase(HDAC) activities may play a causative role in regulating gene expression. 多种具有组蛋白乙酰化酶(HAT)和组蛋白去乙酰化酶(HDAC)活性的调节因子,通过对组蛋白乙酰化过程的调节,在基因表达调控中发挥着重要作用。