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- 抗Fas单抗anti-Fas monoclonal antibody
- 方法小儿急淋白血病细胞分别与Bcl?2反义脱氧寡核苷酸、抗Fas单抗培养,或与两者一起培养,再分别定量检测其凋亡细胞。Methods The percentage of apoptotic cells was detected after childhood ALL cells were incubated with Bcl 2 ASON, anti Fas MoAb or with both of them, respectively.
- 5 -FU、阿霉素能增加GRC- 1肾癌细胞株Fas表达并促进Fas单抗诱导的肾癌细胞的凋亡。5-FU and ADR increased the Fas expression in GRC-1 RCC cell line and enhanced the apoptosis of GRC-1 cells induced by anti-Fas monoclonal antibody (CH11).
- 经 pcDNA3 Fas真核表达载体转染的卵巢癌细胞Fas基因表达及对Fas单抗诱导凋亡的敏感性均有不同程度提高。Transfection of ovarian carcinoma cells with the eukaryotic vector pcDNA3 Fas enhanced cell surface expression of Fas gene and induced susceptibility to Fas antibody mediated apoptosis.
- 结论制备的可溶性抗Fas?Fab抗体具有抗Fas抗体的特异性,为进一步的研究奠定了基础。Anti Fas Fab phage antibody displaying on phage surface and soluble anti Fas Fab showed specific binding activity to Fas by ELISA. Conclusion The successful preparation of anti Fas Fab antibody paved a way for further study and application.
- 抗Fas抗体Anti-Fas antibody
- 目的:研究抗Fas抗体对人肾小球系膜细胞的致凋亡作用,探讨Fas?FasL在肾脏损伤中的作用。Objective:To investigate the mechanism inducing apptosis of human glomerular mesangial cells (Mcs) by anti Fas antibody.
- 抗Fas抗体诱导维甲酸分化后的髓母细胞瘤细胞凋亡All-trans retinoic acid sensitizes human medulloblastoma cells Med-3 to anti-Fas antibody mediated apoptosis
- 单抗monoclonal antibody
- 用重组人Fas抗原进行4轮筛选,得到100%的富集,说明Fas重组抗原富集了抗Fas?Fab噬菌体抗体,经ELISA检测均有抗Fas抗体的特异性。The phage displaying antibody fragments were subjected to four rounds of panning with recombinant Fas antigen at solid phase. The eluted phage was enriched for nearly 100 fold and the percent of recombinant clones increased from 27%25 to 100%25 after four rounds of panning.
- 抗Fas锤头状核酶阻抑小鼠急性粒-单核白血病细胞免疫逃逸的研究Depressing the Immune Escape of Acute Myelomonocytic Leukemia via an Anti-Fas Ribozyme
- 5a8单抗monoclonal antibody to CD4,5a8<接触HIV后的预防药>
- VP1单抗Monoclonal antibody against VP1 protein
- 17-LA单抗monoclonal antibody 17-LA<胰腺癌治疗药>
- CD45单抗CD45 monoclonal antibodies<防器官移植排异药>
- PM-81单抗monoclonal antibodies PM-81<白血病治疗辅助药>
- 阿昔单抗Abciximab
- 埃巴单抗Edobacomab
- 贝伐单抗bevacizumab<免疫调节药>
- 比伐单抗bivatuzumab<免疫调节药>