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- Their activities are inhibited by the tissue inhibitor of metalloproteinase (TIMP). 其活性受到特异性金属蛋白酶抑制剂(TIMP)的抑制。
- Several studies have shown that the MMP-1/TIMP(tissue inhibitor of matrix metalloproteinase) ratio is decreased in hypertensive heart disease. 多项研究表明发生高血压心脏病时MMP-1/TIMP(金属蛋白酶组织抑制剂)比率降低。
- Tissue Inhibitor of Metalloproteinases (TIMPs) is the specific inhibitor of MMPs, and TIMP-1 mainly inhibits the activity of MMP-2 and MMP-9. 金属蛋白酶组织抑制因子(Tissue Inhibitor of Metalloproteinases, TIMPs)是MMPs特异性抑制因子,其中TIMP-1主要抑制MMP-2和MMP-9的活性。
- Objective To explore the effect of Danshao Huaxian Capsules(DHC)in tissue inhibitor of metalloproteinase-1(TIMP-1)expression of rats with liver fibrosis. 目的探讨中药丹芍化纤胶囊对实验性肝纤维化大鼠金属蛋白酶组织抑制因子-1(tissue inhibi- tor of metalloproteinase-1,TIMP-1)表达的影响。
- The tissue inhibitor of metalloproteinases (TLMPs), which is major endogenous regulators of MMP activiesin, play an important role in the matrix synthesis and degradation balance. 基质金属蛋白酶特异性组织抑制剂(tissue inhibitor ofmetalloproteinases,TIMPs)是MMP活性的重要内源性调节因子,在基质合成与降解平衡中发挥重要作用。
- Recent studies have found that homocysteinemia and matrix metalloproteinase and its endogenous tissue inhibitor play important roles in carotid artery stenosis. 最近的研究发现,高同型半胱氨酸血症和基质金属蛋白酶及其内源性组织抑制剂在颈动脉狭窄中起重要作用。
- Objective To examine whether tissue inhibitor of metalloproteinases-1 (TIMP-1) is involved in arterial calcification of chronic renal failure(CRF) rats. 摘要 目的 探讨金属蛋白酶1组织抑制剂(TIMP-1)是否参与慢性肾衰竭大鼠动脉钙化形成。
- Objective To explore the expression and significance of matrix metalloproteinase 9(MMP9) and tissue inhibitor of metalloproteinase 1(TIMP1) in rats with infectious brain edema. 目的探讨基质金属蛋白酶9(MMP9)及组织型基质金属蛋白酶抑制因子1(TIMP1)在大鼠感染性脑水肿中的表达及意义。
- Objective To investigate the relationship between the messenger RNA(mRNA) levels of matrix metalloproteinases(MMP 9, MMP 2) and tissue inhibitor of metalloproteinase (TIMP 1,TIMP 2) and malignant transformation of hydatidiform mole. 目的 探讨基质金属蛋白酶 (MMP 9、MMP 2 )及其组织抑制物 (TIMP 1、TIMP 2 )表达量与葡萄胎恶变的相关性。
- Objective: To explore the role of matrix metalloproteinase 9 (MMP 9) and tissue inhibitor of metalloproteinase 1 (TIMP 1) protein on embryo implantation in unexplained infertile women. 目的 :探讨不明原因不孕妇女子宫内膜种植窗期基质金属蛋白酶 - 9(MMP- 9)及金属蛋白酶组织抑制物- 1(TIMP- 1)的表达对胚胎着床的影响。
- Objective: To investigate the effect of hypoxia on the mRNA expression of tissue inhibitor of metalloproteinases (TIMPs) in breast carcinoma cell line (MDA-231) and the effect of basil polysaccharide (BP) on the expression of TIMPs. 目的:探讨低氧对人乳腺癌细胞株MDA-231金属蛋白酶组织抑制剂(TIMPs)mRNA表达的影响,以及罗勒多糖(basilpolysaccharide,BP)对TIMPs的作用。
- The COC1 expressed the mRNAs of matrix metalloproteinase 2 (MMP-2), tissue inhibitor of metalloproteinase-2 (TIMP-2) and plasminogen activator inhibitor type 1 (PAI-1), but not those of MMP-9, TIMP-1 or urokinase-type plasminogen activator (u-PA). 卵巢癌细胞株COC1表达基质金属蛋白酶2(MMP-2)、基质金属蛋白酶抑制剂(TIMP-2)及纤溶酶原抑制剂(PAI-1),而不表达MMP-9、TIMP-1及尿激酶型纤溶酶原激活物(u-PA)。
- The changes of tissue inhibitor of matrix metalloproteinases (TIMPs)during occurence and development of cardiovascular diseases is one of the hottest research points in cardiovascular field recently. 基质金属蛋白酶组织抑制剂在心血管疾病发生发展过程中的变化是近年来心血管领域研究的热点之一。
- Aim To investigate the mRNA levels of tissue inhibitor of metalloprot einase-1(TIMP-1),tissue inhibitor of metalloproteinase-2 (TIMP-2) in rat car diac fibroblasts by multiplex reverse transcription-polymerase chain reaction ( RT-PCR). 目的通过建立多重反转录聚合酶链反应(RT-PCR)方法,旨在测定大鼠心肌成纤维细胞组织金属蛋白酶抑制剂-1(TIMP-1)、组织金属蛋白酶抑制剂-2(TIMP-2)的mRNA水平。
- Objective To discuss the relationship between matrix metalloproteinases and its tissue inhibitors and tissue fibrosis. 目的探讨基质金属蛋白酶及其抑制因子与组织纤维化的关系。
- Tissue inhibitor of metalloproteinase-2 金属蛋白酶组织抑制剂-2
- tissue inhibitor of metalloprotease 组织金属蛋白酶抑制剂(法)
- tissue inhibitor of metalloproteinase 金属蛋白酶组织抑制剂
- The surgeon cut out all the diseased tissue. 外科大夫把坏了的组织都切除掉。
- tissue inhibitor of matrix metalloproteinase 基质金属蛋白酶抑制剂