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- Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream. 单靠峰时血浆浓度来确定生物利用度会导致误解,因为药物一进入血流就会开始药物消除。
- The MIC 50 of BDP against 690 clinical isolates is 4 mg/l that is lower than the peak plasma concentration which can be achiered after single oral dose of 600 mg BDP. BDP对690株临床分离株的MIC50为4mg·L-1,低于单次口服600mgBDP在血浆中可能达到的峰浓度。
- Capsules opened and sprinkled on applesauce are not bioequivalent to administration of intact capsules under fasting conditions. Peak plasma concentration and AUC are increased by 15% to 20%. 打开胶囊,将内容物撒在苹果酱上,与禁食条件下给予整个胶囊的生物等效性不等,血浆峰浓度与AUC增加15%25-20%25。
- peak plasma concentration 血浆浓度峰值
- No change in plasma concentration of AEDs was observed. 迷走神经刺激术后血浆抗癫痫药物浓度未见明显改变。
- P = .021), reflected in shorter latencies to peak L-dopa plasma concentrations. P=.;021),反映了L-多巴血中浓度在比较短的时间内到达高峰;
- Objective To determine the plasma concentration of glycyrrhetic acid( GA) by HPLC. 目的采用高效液相色谱法测定人血浆中甘草次酸浓度。
- The plasma concentration of BNP was positively correlated with LEVI at the recovery phase(r=0.35,P< 0.01). 血浆脑钠素浓度与恢复期左室容积指数呈正相关r=0.;35;P<0
- Conclusion The plasma concentration of EBV DNA could reflect the tumor burden in patients with NPC. 血浆EBV DNA水平与TV、NV、TNV呈正相关关系。 结论鼻咽癌患者治疗前血浆EBV DNA水平可在一定程度上反映其体内肿瘤负荷。
- The study indicated that it is important for epileptic patients to monitor the plasma concentration of carbamazepine. 结论:卡马西平的血药浓度监测在癫痫治疗中具有重要的临床指导意义。
- Objective To determine the plasma concentration of aminophylline,and design the individuation project. 目的测定氨茶碱血药浓度,并设计个体化给药方案。
- The plasma concentration of CCK was lower than before infusion (p<0.05), but was still higher than normal (p<0.01). 血浆CCK水平较自体胆汁灌输前降低(p<0.;05),但仍高于正常CCK水平(p<0
- There was no significant difference between groups in the plasma concentration of total bupivacaine. 血中布比卡因浓度无统计学差异。
- Objective: To provide a simple and easy fluorimetric assay for plasma concentration of vecuronium. 目的: 提供一种简单易行的维库溴铵血药浓度荧光测定方法。
- Results The plasma concentration of ET, NPY in CRF patients was dramatically higher than that in health group. 结果CRF患者血浆ET、NPY含量明显高于健康组,且尿毒症期明显高于氮质血症期。
- The peripheral vein blood was taken to measure the plasma concentration of cortisone and A-II at 1 hour after incision and at the end of the operation. 术后1h和术毕采外周静脉血,测定血清皮质醇和血清紧张素(A-II)的浓度。
- The plasma concentration of ANP was higher in the fetuses of PIH patients than that in the normal controls, but Aldo was lower. 胎儿血浆中ANP、Aldo均高于母血,PIH胎儿ANP高于正常胎儿,Aldo显著低于正常胎儿。
- The expression of ADM in group B was significantly higher than that in group A (P <0.01) ,but plasma concentration of ADM had no difference. B组肾上腺组织中ADM蛋白的表达明显高于A组(P<0.;01);
- There was no close correlation between MAP, HR and the end-tidal isoflurane concentration, target plasma concentration of propofol. MAP和HR的变化与异氟醚呼末浓度和异丙酚浓度无相关性。
- Many mountaineers have reached that mountain peak. 许多登山家都登上过那座大山的顶峰。