Capsules opened and sprinkled on applesauce are not bioequivalent to administration of intact capsules under fasting conditions. Peak plasma concentration and AUC are increased by 15% to 20%.

 
  • 打开胶囊,将内容物撒在苹果酱上,与禁食条件下给予整个胶囊的生物等效性不等,血浆峰浓度与AUC增加15%25-20%25。
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