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- Positive genotype of RANTES gene promoter -28G may be related to DN. RANTES基因启动子-28G阳性基因型可能与糖尿病肾病相关。
- Partial Deleted Complementary Sense Gene Promoter from Cotton Leaf Curl Virus Shows Super Strong Promoter Activity. 部分缺失的棉花曲叶病毒互补链基因启动子具有超强活性。
- The methylation specific PCR (MSP) and bisulfite DNA sequencing were performed to examine the methylation status of SLIT2 gene promoter. 亚硫酸氢钠处理DNA,用MSP和测序法检测SLIT2启动子甲基化状态。
- Abstract: BACKGROUND: Gene promoter methylation is an epigenetic eent leading to gene silencing. 摘要：背景：基因启动子甲基化是一种可引起基因沉默的表观遗传事件。
- Objective:To construct expression vector of human ID4 gene promoter on the basis of bioinformatics analysis. 目的:基于生物信息学分析构建人ID4基因启动子表达载体,以其作为研究ID4基因启动子表达调控分析的工作基础。
- Methylation of hMLH1 and COX-2 gene promoter CpG islands may both occur in the development of MSI gastric carcinoma. 在MSI胃癌(尤其是MSI-H型胃癌)的发生、发展过程中可能同时出现了hMLH1和COX-2基因启动子CpG岛的甲基化(即表型遗传修饰)。
- Methylation of hMSH2 gene promoter CpG islands was not detected in gastric carcinoma or normal tissues. hMSH2基因启动子CpG岛在胃癌及正常组织中均未检测到甲基化。
- Isolation and Characterization of CMO Gene Promoter from Halophyte Suaeda liaotungensis K. 辽宁碱蓬胆碱单加氧酶(CMO)基因启动子分离及功能元件分析(英文)
- The methylation rate of hMLH1 gene promoter CpG islands in MSI-H was higher than that in MSS (P<0.01). 在MSI-H组hMLH1基因启动子CpG岛甲基化率显著高于MSS组(P<0.;01);
- Cases with methylation of COX-2 and hMLH1 gene promoter CpG islands in gastric carcinoma were 8 and 13, and they were not detected in normal tissues. COX-2和hMLH1基因启动子CpG岛甲基化在43例胃癌中分别有8例和13例,正常组织中未检测到。
- The positive frequency of methylation of P16 gene promoter in HPP-CFC of normal contrasts was higher than that of psoriatic patients. 正常对照骨髓HPP-CFC P16基因启动子甲基化阳性率较高,而银屑病患者骨髓HPP-CFC P16基因启动子甲基化阳性率低于正常人。
- AIM To investigate the relation between methylation of plasma thrombomodulin(TM) gene promoter and coronary heart disease(CHD). 目的探讨血栓调节蛋白(thrombomodulin,TM)基因启动子甲基化与冠心病(CHD)的关系。
- The constructed wild type p21 gene promoter driven luciferase repo rter plasmid is used to transfect ECV304 cells to express luciferase protein sta bly and reliably. 构建的野生型p21基因启动子驱动的荧光素酶报告基因载体,转染ECV304细胞后能够表达荧光素酶蛋白,具有稳定和可靠性能。
- Methods The methylation status of CpG island of AR gene promoter in 3 leukemic cell lines and 15 leukemic bone marrow cells was detected by methylation specific PCR(MSP). 方法应用甲基化特异性PCR技术(methylation specific PCR,MSP)检测3种白血病细胞株及15例患者骨髓标本雄激素受体基因甲基化状态。
- The high transcriptional activity of hTERT gene promoter in MCF7 cell indicates its potential utility as a novel candidate for transcriptional targeting of breast cancer. hTERT启动子在乳腺癌MCF7细胞中具有很强的特异性,为进一步开发肿瘤的特异性基因治疗奠定实验基础。
- The HPO gene promoter might represent a novel architecture for core promoters. 这一发现对了解此类基因的转录起始具有一定的指导意义。
- Another study employed the AFP gene promoter for gene therapy against high AFP-secreting hepatoma cells using a retrovirus vector carrying a herpes simplex thymidine kinase gene . 另一研究通过携带单纯性疱疹病毒胸腺嘧啶激酶基因（的逆转录病毒载体，使用AFP基因启动子基因治疗高AFP分泌肝细胞瘤。
- Objective: To determine the association between the human SLC6A4 gene promoter polymorphism and the Chinese people with antisocial personality disorder(APD). 目的:探讨中国汉族人群SLC6A4基因启动子区基因多态性与反社会人格障碍的关系。
- Another study employed the AFP gene promoter for gene therapy against high AFP-secreting hepatoma cells using a retroirus ector carrying a herpes simplex thymidine kinase gene . 另一研究通过携带单纯性疱疹病毒胸腺嘧啶激酶基因（的逆转录病毒载体，使用AFP基因启动子基因治疗高AFP分泌肝细胞瘤。
- Using suitable enzymes to cut the plasmid pRA-9 and pGEM-T Easy, we recovered the fragments of Actinidin gene promoter (1.3kb) and ipt gene (0.72kb). Then linked these two fragments with pBI121 plasmid and transformed it into E. PCR检测结果表明转化质粒pBI 121一Actinidin一iPt可以扩增出1 .;3kb明亮的目的片断，分别用Xbal与BamHI和Ba]卫Hl与Sacl双酶切转化质粒，电泳结果显示转化质粒被成功的切出了1
