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- Methods: Cholesterol(50.00 mg/L) was used on human umbilical endothelial cell line,ECV304,48 h later,cell genomic DNA methylation level was detected by HPLC. 方法:体外培养人脐静脉血管内皮细胞ECV304;以50.;00 mg/L的胆固醇作用于ECV304 48 h;提取细胞基因组DNA;用高效液相色谱法(HPLC)检测基因组DNA甲基化水平。
- After fusion of cytoplasm, the DNA methylation levels of the fused embryos was very high as well as two-cell diploid embryos in vivo. 在细胞核开始融合的时候，甲基化水平急速下降，在细胞核完全融合的时候甲基化水平达到最低点；
- DNA methylating inhibitor makes the transfer of the methyl group to adenine or cytosine impossible,thus the reaction of DNA methylation is inhibited,the genomic methylation level is decreased. DNA甲基化抑制剂使甲基基团不能转移到腺嘌呤或胞嘧啶,导致DNA甲基化反应受阻,从而使基因组甲基化水平降低。
- Effects of Heavy Metal on the DNA Methylation Level in Rice and Wheat 重金属对水稻和小麦DNA甲基化水平的影响
- Change of total genomic DNA methylation level in human hepatocellular carcinoma 人原发性肝细胞癌中总基因组DNA甲基化变化的研究
- Vernalization and Its Relation to DNA Methylation Level in Radish (Raphanus Sativus L.) 萝卜春化作用及其与DNA甲基化水平的关系
- Analysis of Genomic DNA Methylation Level in Radish under Cadmium Stress by Methylation-sensitive Amplified Polymorphism Technique 镉胁迫下萝卜基因组DNA甲基化敏感扩增多态性分析
- Keywords Soil Naphthalin Pollution Stress;Content Of Chlorophyll;Photosynthesis;Catalase Ctivity;Root Activity;CAT Activity;Endogenous Hormone;Corn Quality;DNA Methylation Level; 土壤萘污染;根系活力;CAT;叶绿素;光合速率;内源激素;玉米品质;DNA甲基化;
- The conformational change of M. L. DNA with different methylation level was measured by CDD and UVD spectra. L.;DNA分离出来
- Focus on the bioinformatics analysis of DNA methylation. 甲基化的生物信息学分析。
- DNA methylation is a frequent change in epigenetics of leukemia. 摘要DNA甲基化是白血病表观遗传学改变中较常见的改变。
- DNA methylation plays a key role in transgene silencing. DNA甲基化是引起外源基因沉默的主要原因。
- DNA methylation and its aberrance play an important role in the human development and tumorigenesis. DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。
- DNA methylation patterns in the CpG island of RASGRF2, RASGRF2 and FBN2 were determined by the method of MSP. 采用 MSP分析 RASSF1A、 RASGRF2 和 FBN2 是否存在启动子异常甲基化。
- Alterations in DNA methylation, an important regulator of gene transcription, lead to cancer. 对调节基因转录起重要作用的DNA甲基化的异常将导致癌症的发生。
- Recent studies on DNA methylation and its regulatory enzymes,seem hot to researches of epigenetics. DNA甲基化及其调节酶是近年来表观遗传学研究的热点。
- Both MSAP (methylation sensitive amplification polymorphism) ratio and full methylation level were the highest in bracteal leaf, and the lowest in tassel. 同一组织在两个自交系中的甲基化水平也存在差异。
- The abnormality of DNA methylation includes global hypomethylation and region-specific hypermethylation. DNA甲基化异常包括全基因组的低甲基化和局部基因的高甲基化。
- The advent of microarray technology has provided new opportunities for high-throughput study on DNA methylation. 芯片技术的发展为高通量研究DNA甲基化提供了新的方法。
- DNA methylation is a kind of normal endogenous modified mode,which is fulfilled by DNA methylation transferase. DNA甲基化是真核生物DNA的正常内源性修饰方式,它由DNA甲基化转移酶催化发生。
