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- CD40LCD40 ligand
- CD40-CD40LCD40-CD40L
- CD154Anti-CD154
- 可溶性CD40LsCD40L
- 可溶性CD154sCD 154
- CD40L在川崎病发病机制中的作用探讨The roles of CD40 ligand in the pathogenesis of Kawasaki disease
- CD154／CD40LCD154/CD40L
- CD154单克隆抗体CD154 mAb
- CD28与CD40／CD154co-stimulatory molecules
- CD40L异常表达及血清中E-选择素在川崎病发病机制中起重要作用。CD40L and E-selection might play a role in the immunopathogenesis of KD.
- 共刺激分子CD40/CD40L和OX40/OX40L在乳腺癌中的表达及其生物学意义The Expression of Co-stimulators CD40/CD40L and OX40/OX40L and Their Biological Roles in Human Breast Cancer
- D组联合应用CD4+ CD25+ T细胞和CD154单抗。group D, CD4+ CD25+ Treg in combination with anti-CD154 was given.
- 川崎病患儿CD4+T细胞表面CD40L表达与E-选择素水平正相关(r=0.626,P<0.05)。There was a significantly positive correlation between CD40L expression on CD4+T-cells in patients with KD and E-selection(r=0.626, P<0.05).
- 采用国内外公认的对人具有明显免疫增强作用的CpG2006，通过分子偶联技术合成CpG2006复合物(CD40L-pLL-CpG2006)。Applied FACS to assess the uptake rate of CpG2006 and to analysis the expression level of CD 19, CD20, CD22 and CDS.
- 与正常人对照相比,SLE外周血B淋巴细胞中CD154诱导NF-资B核转移存在显著异常,类似生发中心表型。CD154-induced NF-kB nuclear translocation is abnormal in human lupus B lymphocytes with phenotype analogous to germinal center B cells.
- CD3+T细胞上CD154表达的PPC,刺激前健康老年组高于健康青年组(P<0.05),低于老年肺炎组(P<0.05);Without stimulation,the PPC of CD154 on T cell in the aged control group was significantly higher than that in the young control group(P<0.05),but lower than that of the aged pneumonia group(P<0.05).
- 术前输注供体来源的IL-12 p35 silenced DC联合CD40L mAb,可在一定程度上抑制小肠移植的排斥反应,诱导受体产生免疫耐受。The treatment with IL-12 p35 silenced DCs with anti-CD40L mAb can induce immune tolerance and prolong intestinal allografts survival after transplantation.
- RA患者CD4+T细胞上CD154分子表达增加,CD8+T细胞上CD154分子表达减少,T细胞亚群上可诱导共刺激分子(ICOS)的表达无明显变化;CD154 on RA CD4~+T cells was increased but decreased on RA CD8~+T cells. The expression of ICOS on T cell subsets was similar to that of normal control;
- 方法采用流式细胞技术检测SLE、RA患者外周血T细胞亚群表面CD28、CD152、诱导性共刺激因子(ICOS)、CD154、CD30和CD95分子表达。Methods Apply flow cytometry to determine the expressions of costimulators CD28,CD152,ICOS,CD154,CD30 and CD95 on T lymphocyte subsets in patients with SLE and RA.
- 目的:研究CD154在膀胱移行细胞癌(TCC)中的表达及其与肿瘤临床分期和病理分级之间的关系,并通过体外细胞培养以及小鼠膀胱肿瘤模型研究CD154的表达对膀胱TCC成瘤性的影响。Objectives: To investigate CD154 expression in transitional cell carcinoma(TCC) of bladder and its correlation with tumor stage and tumor grade,and further to explore its effects on tumorigenesis by in vitro and in vivo experiments.
