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- Bicistronic adenovirus 双顺反子溶瘤腺病毒
- Adenovirus mediated angiostatin gene therapy for rat glioma. 重组腺病毒载体介导血管抑素基因治疗大鼠脑胶质瘤的实验研究。
- Adenovirus and parainfluenza virus are common viruses in the community. 腺病毒及副流感都常见于社区。
- Results The bicistronic eukaryotic expression plasmid was corrected and can co - express human BMP -2 and VEGF165 mRNA in vitro. 该重组质粒能在体外同时表达BMP2及VEGF165 mRNA。
- Results showed that IRES was superior to SV40 promoter for guarantee of genes co expression in bicistronic retrovirus mediated gene therapy. 结果表明:在双基因逆转录病毒载体介导的小鼠骨髓细胞的基因转导中,IRES与内部SV40启动子相比,更能保证双基因的共同表达。
- The patterns of DNA of these viruses are similar to that of enteric adenovirus( EAd). 这些腺病毒DNA的电泳图型类似于肠道腺病毒。
- ALR gene was also inserted to bicistronic plasmid p! RES2-EGFP to produce ALR, EGFP gene bicistronic eukaryotic expression vector (pIRES-EGFP/ALR). ALR和EGFP基因双顺反子表达载体,pIRES-EGFP/ALR。
- Cytokine expressing plasmids pcDNA3/GM-CSF and pcDNA3.1(-)/IL-4 and , bicistronic plasmid pGM-CSF/pTPA-E were constructed. 构建小鼠细胞因子表达质粒pcDNA3/GM-CSF和pcDNA3.;1(-)/IL-4,以及双表达质粒pGM-CSF/pTPA-E;用细胞因子表达质粒分别与VR1020/E共同免疫小鼠,分析细胞因子质粒对AMA1 DNA免疫的调节作用。
- Adenovirus is the main candidate for expressing and delivering therapy genes because of its intensive tissue tropism. 因其具有广泛的组织亲和性,腺病毒成为表达和传递治疗基因的主要候选者。
- Laboratory tests for three of discharged patients showed adenovirus in 2 and parainfluenza type 3 in one. 三名出院病人的化验显示,其中2名为腺病毒,另一名为副流感3型。
- Objective To characterize the intertype epitopes on human adenovirus (HAdV) hexon. 目的 对人类腺病毒 (adenovirus,AdV)六邻体型间抗原位点的特性进行研究。
- Objective To study the therapy for C6 glioma with therecombinant adenovirus containing angiostatin eDNA (AdhCMV-AGS). 目的:构建重组缺陷型腺病毒血管抑素基因(angiostatin)载体,进行血管抑制基因治疗脑胶质瘤的体内及体外的实验研究。
- The recombinant adenovirus is successfully constructed and can efficient express EWS/FLI1 in PBMC. 重组腺病毒AdEWS/FLI1构建成功 ,并能在PBMC中稳定有效地表达 ,为进一步进行尤文肉瘤的免疫治疗研究奠定了基础。
- Gendicine uses an adenovirus as a carrier, or vector, to take tumour-suppressing DNA directly to a tumour. 基因药物通过利用腺病毒作为载体,或称为带菌体,直接携带可抑制肿瘤的DNA接近肿瘤。
- Methods The kidney of SD rats were transfected with CTLA4-Ig gene-recombined adenovirus. 方法以CTLA4-Ig基因重组腺病毒为载体,将CTLA4-Ig基因局部转染入SD大鼠肾脏。
- Pancreatic adenocarcinoma cells(BxPC-3, AsPC-1) were infected with adenovirus Ad-mEndo. 腺病毒Ad-mEndo在体外分别感染胰腺癌细胞株BxPC-3、AsPC-1,观测其体外转染及内皮抑素表达情况;
- Specific Expression of Suicide Gene in Liver Cancer?Cells Mediated by Adenovirus ?? 腺病毒载体介导的肝癌细胞专一性自杀基因表达
- Conclusion:The infection efficiency of adenovirus is determined by the levels of CAR and integrin on cancer cells. 结论:肿瘤细胞表面CAR和整合素的表达水平决定了腺病毒对肿瘤细胞的感染效率。
- The paper says at least 10 people have been killed by a variant of the strain known as adenovirus 14. 这篇文章宣称,有至少10人被这种叫做腺病毒14的各种变形病毒致死。
- Mouse marrow stromal cells (MSCs) was transfected with this bicistronic eukaryotic expression plasmid using lipofecarmin reagent The expression of BMP -2 and VEGF165 were detected by RT - PCR. 进行酶切分析及序列测定后,用脂质体体外转染小鼠骨髓基质细胞,RT-PCR检测BMP2及VEGF165的表达。 结果:核酸序列测定证实重组质粒构建正确;
