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- A second \'deliberate\' mechanism is called replicative senescence or cellular senescence. 第二个\\'故意\\'的机制被称为复制性衰老或细胞衰老。
- But this hypothesis fails because replicative senescence is far older than cancer. 但这一假说失败了,因为复制衰老比癌老得多。
- Many invertebrates experience replicative senescence, though they never die of cancer. 许多无脊椎动物经历复制衰老,虽然它们从来没有死于癌症。
- The study of the relationship between telomere-related factors and cell replicative senescence contributes to elucidate the mechanism of aging. 近年来的研究发现,端粒长度的缩短是造成细胞复制性衰老的原因,而端粒的长度受端粒相关因子的调节。
- For replicative senescence in one-celled organisms, telomeric ageing is clearly a \'feature\' of the genetic software, not a bug. 对单细胞生物体的复制性衰老而言,端粒的老化显然是基因程序的一个\\'特点\\',而不是基因程序上的一个瑕疵。
- Objective To investigate the effects of HDTIC-1 and HDTIC-2 isolated from Astragali Radix on the expression of p16 and p21 of human fetal lung diploid fibroblasts(2BS) so as to explore the mechanism of HDTIC delaying replicative senescence. 目的观察黄芪碱化合物HDTIC-1和2对人胚肺二倍体成纤维细胞(2BS)p16、p21表达的影响,以探讨其延缓复制性衰老的分子机制。
- Biomarkers of replicative senescence were assess in this model. The averages of life span of IMR 90 under NG,LG and HG culture conditions were 55 0,58 3 and 47 2 population doubling levels(PDL),respectively. 低、正常和高浓度葡萄糖培养条件组IMR 90细胞平均寿限分别为 5 8 3、5 5 0和 4 7 2PDL(群体倍增水平 ) .
- Keywords caloric restrction;cellular replicative senescence;human diploid fibroblast IMR 90; 热量限制;细胞复制衰老;人二倍体成纤维细胞IMR-90;
- Keywords Chondrocyte Replicative senescence Cell cycle Proliferation Phenotype Rat; 软骨细胞;复制性老化;细胞周期;增殖;表型;大鼠;
- Keywords replicative senescence;2BS;subtractive hybridization;differentially expressed genes; 关键词复制性衰老;2BS;消减杂交;差异表达基因;
- Keywords Telomere restrict fragment Normal parotid Normal epidermis Cell replicative senescence; 端粒限制性片段长度;正常腮腺;正常皮肤表皮;细胞复制性衰老;
- Keywords Natural Cerebrolysin;Human embryonic lung diploid fibroblasts;Proliferation activity;Delay;Replicative senescence; 天然脑活素;人胚肺成纤维细胞;增殖活度;复制性衰老;延缓;
- 3Smith JR, PereiraSmith OM. Replicative senescence: implications for in vivo aging and tumor suppression[J]. Science, 1996, 273(5271): 6367. 5姚明忠;顾文聪.;固真方对老年大鼠肝脏原癌基因和抗癌基因表达的影响[J]
- replicative senescence 复制性衰老
- Keywords hTERT;RNAi;proliferation;replicative senescence;apoptosis;TRAIL;telomere;telomerase;apoptosis-associated protein;gastric carcinoma;hepatocellular carcinoma;colon carcinoma; 人端粒酶逆转录酶;RNA干扰;增殖;衰老;凋亡;TRAIL;端粒;端粒酶;凋亡相关蛋白;胃癌;肝癌;结肠癌;
- Eth accelerated the senescence of cut flowers. 0.;3mmol/LSTS脉冲液在常温下对延长切花寿命没有明显作用。
- Is that picture original one or replicative one? 那幅画是原作还是复制品?
- Senescence is the key problem of cucumber storage. 衰老是黄瓜贮藏中的主要问题。
- It affects tuberization, leaf senescence, and dormancy. 它影响块茎形成、叶子衰老和休眠。
- And cheating cell senescence probably wouldn't grant immortality. 就算骗过了细胞老化的过程,大概不能保证长生不老。