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- After binding to the replication origin, ORC provide a pad for the other initiation factors (such as cdc6, Cdt1, MCM2-7) to conform the pre-replicative complex (pre-RC). 当ORC与DNA的复制起始位点特异结合后,形成一个平台,之后cdc6、Cdt1及MCM2-7相继结合到ORC上,形成复制前复合物。
- DnaA, the replication initiator in the bacterium Escherichia coli, is monomeric in solution and oligomerizes upon binding to multiple initiator sites at a replication origin(5). 作为细菌大肠杆菌的复制起始子,在复制起点,它是“融解”过程的一个单体并且当其结合到多个起始子位点时会发生寡聚化。
- The three strategies to construct HAC have been explored without full knowledge of chromosome elements such as centromere,telomere and replication origin. 本文探讨了在不完全了解着丝粒、复制起始点、端粒等人类染色体基本功能单位的情况下构建HAC的三种策略。
- In bacteria, archaea, and lower eukaryotes, the unwinding process begins at a sequence called the replication origin, which contains several conserved binding sites for a protein called the initiator. 在细菌、原生生物和低等真核生物中,解链过程开始于一个被称作复制起点的序列,它包括几个蛋白质(起始子)保守结合位点。
- But like those of bacteria, the replication origins of archaea contain several conserved initiator binding sites positioned near an A and T-rich unwinding element (10). 但像那些细菌一样,原生生物的复制起点则包含着几个位于富含A、T解链元素附近的保守的起始子结合位点。
- A DNA Autonomous Replication Origin with Promoter Function in Yeast 一个具有启动子功能的酵母DNA自主复制起始区
- A number of studies reported there are unusual clusters of palindromes, closely spaced repeats and inverted repeats in the neighborhood of the replication origins of herpesviruses. 据 大量的研究报道,在疱疹病毒的复制起源点附近有难得的回文,近距离重复,和反向重复结构。
- The illness is organic in origin. 该病起初是器质性疾患。
- Its origin is wrapped in mystery. 它的起源仍是个未解的谜。
- The apparent celestial origin of a meteoric shower. 流星群的辐射点明显的流星雨太空光源
- Each of the CDs is packaged with replicated original UK album art, including expanded booklets containing original and newly written liner notes and rare photos. 每个光盘的包装与推广原英国专辑封面,其中包括扩大小册子原来和新载的书面说明和罕见的班轮照片。
- The vase seems to have an orient origin. 这花瓶好像来自东方。
- The origin of the universe is an ageless topic. 关于宇宙的起源的问题是个永恒的论题。
- A protease is key to the replication of the virus. 蛋白酶是阻止非典病毒变异的关键物质。
- He flew high though he was of humble origin. 他虽出生低微,却胸怀大志。
- What was the origin of the quarrel? 这场争吵的起因是什么?
- Cloning and functional studies of the chromosomal replication origin of Actinomadura yumaensis 尤马马杜拉放线菌染色体复制区的克隆及功能分析
- A muscle with two heads or points of origin. 二头肌起端有两个头或端的肌肉
- Cloning and Study on the Replication Origin of the Integrated F Plasmid in Escherichia colt 大肠杆菌中整合状态的F′质粒复制起点的克隆和分析
- The replication operation failed. 复制操作失败。