DnaA, the replication initiator in the bacterium Escherichia coli, is monomeric in solution and oligomerizes upon binding to multiple initiator sites at a replication origin(5).

• 作为细菌大肠杆菌的复制起始子，在复制起点，它是“融解”过程的一个单体并且当其结合到多个起始子位点时会发生寡聚化。