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- OBJECTIVE: The renal interstitial fibrosis(RIF) is almost the common pathway by which all the various chronic kidney diseases (CKD) progress to end stage renal disease(ESRD). 目的：肾间质纤维化(RIF)是各种不同病因的慢性肾脏病(CKD)随着病程进展进入终末期肾病(ESRD)的一个进行性、不可逆的共同途径。
- Renal interstitial fibrosis plays an important role in diabetic nephropathy,and epithelial-to-mesenchymal transition(EMT) may be the key step. 肾小管病变及肾间质纤维化在糖尿病肾病中的重要作用逐渐被认识,其中肾小管上皮细胞向间充质细胞转化(EMT)可能是其发挥作用的关键环节,与肾间质纤维化的程度相平行。
- Conclusion tetrandrine, tetramethylpyrazine and amygdalin may play important roles in prevention and reversion of renal interstitial fibrosis. 结论汉防己甲素、川芎嗪、苦杏仁甙在预防及逆转肾间质纤维化中起重要作用。
- CONCLUSION: Decoction of BSHXXZ could markedly improve renal function and delay the progression of glomerulosclerosis and renal interstitial fibrosis. 结论：补肾活血泄浊汤能够明显保护病鼠肾功能，明显减轻病鼠细胞外基质沉积，延缓病变肾小球硬化的发生。
- Gao YL, Chen YP, Dong HR, et al. Experimental study on renal interstitial fibrosis of chronic aristolochic acid nephropahty in rats. Chin J Nephrol2005;21(1):31-35. 高艳丽;谌贻璞;董鸿瑞;等.;慢性马兜铃酸肾病肾间质纤维化发病机制的初步探讨
- Abstract： Objective To study the mechanism of renal interstitial fibrosis after unilateral ureteral Obstruction and effects of enalapril on the process of the fibrosis. 摘 要： 目的 研究单侧输尿管梗阻后肾间质纤维化发生机理及血管紧张素转换酶抑制剂依那普利对其的调节作用。
- Now many stata showed that endothelin had powerful effect on renal of physiology or pathology,which took part in the occurrence and development of renal interstitial fibrosis. 有研究表明,内皮素作为细胞因子之一参与了肾间质纤维化的发生和发展,而内皮素受体拮抗剂通过拮抗内皮素的作用,而发挥肾保护作用。
- Objective Investigate the protective and therapeutic effect of Yishenhuoxueqingli recipe on renal interstitial fibrosis of unilateral ureteral obstruction(UUO)rats. 目的探讨依据益肾活血清利法组方对进展性肾间质纤维化的防治作用。
- Objective:To study the influence of total salvianolic acid(TSA) on the renal interstitial fibrosis caused by unilateral ureteral obstruction (UUO) in rats. 目的观察丹参总酚酸对单侧输尿管梗阻(UUO)大鼠肾间质纤维化的影响。
- Objective To investigate the relationship between renal biopsy pathology (RBP) and spiral CT dynamic contrast scanning (SCTDCS) in renal interstitial fibrosis (RIF). 目的通过不同程度肾间质纤维化(RIF)肾穿刺病理检查(RBP)与螺旋CT薄层动态增强扫描(SCTDCS)对照,探讨RIF病理与螺旋CT诊断指标之间的相关性。
- To investigate the expression of matrix metalloproteinase-9/tissue inhibitor of matrix metalloproteinase-1(MMP9/TIMP1)in rats with renal interstitial fibrosis and the mechanism of renal regulation of "Fu fang bie jia ruan gan fang". 目的探讨基质金属蛋白酶9/基质金属蛋白酶组织抑制剂(1MMP-9/TIMP-1)在肾间质纤维化中的表达情况及其复方鳖甲软肝方的调节作用。
- Deng YY, Chen YP, Hu ZY, et al.The mechanism of renal interstitial fibrosis after unilateral ureteral obstuction in rats and effect of enalapril on this process[J].Chin J Nephrol, 2000, 16(4): 234-7. [2]邓跃毅;陈以平;胡仲仪;等.;单侧输尿管梗阻后肾间质纤维化的产生机制及依那普利对其调节作用[J]
- chronic renal interstitial fibrosis 慢性肾-间质纤维化
- Keywords Astragalus Angelica Renal interstitial fibrosis PDGF-B; 黄芪;当归;肾间质纤维化;血小板源性生长因子-B;
- Role of hepatocyte growth factor in renal interstitial fibrosis in unilateral ureteral obstruction rats 肝细胞生长因子在大鼠肾间质纤维化中作用机制的研究
- Role of hypoxia stimulated expression of connective tissue growth factor in renal interstitial fibrosis 低氧刺激结缔组织生长因子表达与肾间质纤维化
- Relationship between mast cells and renal interstitial fibrosis in interstitial nephritis 肥大细胞与间质性肾炎间质纤维化的关系
- Expression and modulation of connective tissue growth factor in renal interstitial fibrosis 结缔组织生长因子在肾间质纤维化中的表达及其调控
- Keywords Kurarinone;renal interstitial fibrosis;renal tubular epithelial cell-mesenchyma trans-differentiation; 苦参素;肾间质纤维化;肾小管上皮细胞-间质转分化;
- Keywords Sargassum fusiforme （Harv.）Setchell;unilateral ureteral obstruction;renal interstitial fibrosis; 羊栖菜;单侧输尿管梗阻;肾间质纤维化;
