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- pergolide mesilat 甲磺酸硫丙麦角林
- FDA today is issuing a Public Health Adisory (PHA) detailing the remoal of pergolide products from the market. FDA今天发布公共健康忠告,详细说明了培高利特撤市的情况。
- The remoal of pergolide products is not expected to adersely affect patient care because of the alternatie therapies aailable. 培高利特的撤市希望对患者的治疗不会产生不利的影响,因为有其它的治疗药物可选择。
- Conclusions In this study, use of the dopamine agonists pergolide and cabergoline was associated with an increased risk of newly diagnosed cardiac-valve regurgitation. 结论:研究发现使用多巴胺受体激动剂培高利特和卡麦角林可增加新发生的心脏瓣膜返流的风险。
- Raw Material Medicine: Methyltestosterone, Atenolol, Nimodipine, Timolol Maleate, Methadone HCL, Verapamil HCL, Pergolide Mesylate, are all comply with USP/BP/EP standards. 原料药:甲基睾丸素、阿替洛尔、尼莫地平、马来酸噻吗洛尔、盐酸美沙酮、盐酸维拉帕米、甲磺酸培高利特,均符合国际标准。
- In this study, use of the dopamine agonists pergolide and cabergoline was associated with an increased risk of newly diagnosed cardiac-valve regurgitation. 研究发现使用多巴胺受体激动剂培高利特和卡麦角林可增加新发生的心脏瓣膜返流的风险。
- Conclusions In this study, use of the dopamine agonists pergolide and cabergoline was associated with an increased risk of newly diagnosed cardiac-ale regurgitation. 结论:研究发现使用多巴胺受体激动剂培高利特和卡麦角林可增加新发生的心脏瓣膜返流的风险。
- Kucukatay V, Balkan S, Yaras N, et al. The effect of pergolide on cognitive performance of young and middle-aged rats[J]. Int J Neurosci,2002,112(9): 1027. 周杰明;赖世隆;胡镜清;等.;补肾益智法对卵巢切除大鼠学习记忆的影响[J]
- Results Of31 case patients with newly diagnosed cardiac-valve regurgitation,6 were currently exposed to pergolide,6 were currently exposed to cabergoline, and19 had not been exposed to any dopamine agonist within the previous year. 结果:有31例患者出现新诊断的心脏瓣膜返流,其中6例研究时正在服用培高利特,6例使用卡麦角林,另外19例在研究的前一年中未再使用任何多巴胺受体激动剂。
- Of 31 case patients with newly diagnosed cardiac-valve regurgitation, 6 were currently exposed to pergolide, 6 were currently exposed to cabergoline, and 19 had not been exposed to any dopamine agonist within the previous year. 有31例患者出现新诊断的心脏瓣膜返流,其中6例研究时正在服用培高利特,6例使用卡麦角林,另外19例在研究的前一年中未再使用任何多巴胺受体激动剂。
- The frequency of clinically important valve regurgitation was significantly increased in patients taking pergolide or cabergoline, but not in patients taking non?ergot-derived dopamine agonists, as compared with control subjects. 与对照组相比,服用培高利特或者卡麦角林的患者临床上发生重要瓣膜返流的频率显著增加,但服用非麦角??生的多巴胺受体激动剂的患者瓣膜返流的发生率却未增加。
- Patients treated with ergot derivatives who had grade 3 to 4 regurgitation of any valve had received a significantly higher mean cumulative dose of pergolide or cabergoline than had patients with lower grades. 在服用麦角??生物进行治疗的患者中,发生任何瓣膜3到4级返流的患者服用培高利特或卡麦角林的平均累积剂量显著高于瓣膜返流级别较低的患者。
- Pergolide is in a class of medications called dopamine agonists and is used with leodopa and carbidopa to manage the symptoms (tremors and slowness of moement) of Parkinson's disease. 培高利特属于多巴胺激动剂,与左旋多巴和卡比多巴同时应用,用于控制帕金森氏症症状(震颤和运动迟缓)。
- Permax was approed in 1988 for Eli Lilly and Company as an adjunctie therapy with leodopa in Parkinson's disease. alular heart disease was first described in association with pergolide in 2002. Permax是伊莱利利公司于1988年获得批准的、作为辅助治疗药物与左旋多巴用于帕金森氏症的治疗。
- Effect of Pergolide and L-dopa on PC12 Cells Induced by MPP~+ 培高利特和左旋多巴对MPP~+诱导的PC12细胞的作用
- Keywords Bromocriptine;Prolactin;Prolactinoma/drug therapy;Pergolide; 溴隐停;泌乳素;泌乳素腺瘤/药物疗法;培高利特;
- Keywords Parkinson disease;Levodopa;Dopamine agonists;Bromocriptine;Pergolide; 帕金森病;左旋多巴;多巴胺激动剂;溴隐亭;培高利特;
- Efficacy and safety of pergolide mesylate in combination with compound levodopa in treatment of Parkinson'disease 甲磺酸培高利特与复方左旋多巴治疗帕金森病的疗效与安全性
- Keywords ergot derivative dopamine agonists;pergolide;cabergoline;bromocriptine;valvular heart disease;5-HT2B receptor; 麦角碱类多巴胺受体激动剂;培高利特;卡麦角林;溴隐亭;心瓣膜病;5-HT2B受体;
- The rate of cardiac-ale regurgitation was increased with current use of pergolide (incidence-rate ratio, 7.1; 心脏瓣膜返流的发生率由于当前使用培高利特(发病率,7.;1;