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- The NF1 tumor suppressor encodes a protein product neurofibromin,which functions as a negative regulator of RAS. NF1为肿瘤抑制基因,是RAS的负向调节器。
- The negative regulator is simply a unity-gain inverter withinput resistor, R6, and feedback resistor, R7. 负电源整流部分就是一个简单的单位增益反相器,输入电阻是R6,反馈电阻是R7。
- Cyclin is the positive regulator which activates CDK and CDK inhibitor (CDKI) is the negative regulator which inactivates CDK. CDK抑制剂(CDKI)则是负调节因子使CDK失活。
- HAMP encodes a kind of small peptide called hepcidin which is a negative regulator of iron absorbtion in the small intestine and iron release from macrophages. HAMP基因编码一种名为海帕西啶的小肽,是小肠铁重吸收和巨噬细胞铁释放的负调节因子。
- PTP is a negative regulating factor in the MAPK pathway. MAPK级联途径参与有机体的发育、细胞增殖、激素调节以及逆境胁迫的信号转导, PTP在MAPK级联途径中主要起负调控作用。
- CKI plays a negative regulatory role by inhibiting the activity of cyclin-CDK. 细胞周期调节蛋白在细胞周期中的表达和作用已成为当今研究的热门话题。
- Negative regulation involves the binding of a repressor to the operator to prevent transcription. 在负向可诱导操纵子中,一个调节的阻遏蛋白质一般会与操纵基因结合,并阻止操纵子中基因的转录。若存在着一个诱导物分子,它会与阻遏基因结合,并改变它的构造,使它不能与操纵基因结合。这可以使操纵基因的转录发生。
- It is suggested that flavonoids act as negative regulators of auxin transport in vivo. 植物体内广泛存在的类黄酮类物质影响生长素运输,对生长素运输起负调控作用。
- HIR/HIRA,encoded by Hir/Hira(histone regulation) genes,were identified as negative regulators of histone gene expression. H ir/H ira基因产物是组蛋白基因表达的一种负调节因子;其在果蝇发育过程中的作用还没有得到确认.
- While tumor suppressing genes p53 and WT1 present negative roles in hTERT expression, including other negative regulators: MZF-2 and Mad. 另外,p53、WT1、MZF-2和Mad是已知的对hTERT的转录起抑制作用的因子。
- HIR/HIRA, one of the histone chaperones, encoded by Hir/Hira (histone regulation) genes, were initially identified in yeast as negative regulators of histone gene expression. 摘要Hir/Hira基因产物HIR/HIRA为组蛋白的伴侣蛋白,最先作为组蛋白基因表达的一种负调节因子从酵母中被鉴定出来。
- HIR/HIRA,one of the histone chaperones,encoded by Hir/Hira(histone regulation) genes,were initially identified in yeast as negative regulators of histone gene expression. Hir/Hira基因产物HIR/HIRA为组蛋白的伴侣蛋白,最先作为组蛋白基因表达的一种负调节因子从酵母中被鉴定出来。
- The locomotion of mtm-5 gene knockout group is obviously faster than control group, this suggests that MTM-5 also plays a negative regulation role in the muscle development. mtm-5基因敲除型线虫的运动能力明显比对照组快,暗示其可能与肌肉系统以及整体的发育存在着某种负调控的联系。
- The answer to my request was in the negative. 对我的请求的答复是否定的。
- Objective: The p33INGlb was first cloned in 1996. It involved in some biological functions, such as negative regulation of cell proliferation and in the control of cellular aging, anchorage dependence and apoptosis. 目的:p33ING1b是1996年被发现的,它具有多种生物学功能,在细胞生长的负调控、增殖、衰老、肿瘤的锚着依赖性生长、凋亡及细胞周期调控点的调节等方面发挥作用。
- The expression of p16 and Rb protein were significantly correlated with the Dukes staging,especially with stage B.Conclusionp16 and Rb protein make a negative regulation in the P16/CDK/cyclinD/Rb/E 2F pathway. p16蛋白与Rb蛋白表达与Dukes分期显著相关 ,B期表达较C、D期为高。
- P27Kipl is a multifunctional cyclin depedent kinase inhibitor (CKI) that was found recently, and to be regarded as a negative regulative restraining gene of cyclin depedent kinase( CDK) for cell cycle. P27Kipl是近年发现的一个多功能细胞周期蛋白依赖激酶抑制剂(CKI),作为CDK的抑制因子对细胞周期实行负调控。
- CD152, a ligand expressed on the surface of the activated T cells that inhibits co-stimulatory signals, is associated with negative regulation of T-cell activation in the antigen-presenting process. CD152是表达于活化T细胞表面的共刺激信号抑制配体,与抗原递呈过程中T细胞活化的负调控有关。
- His answer to my request was a negative. 我的请求遭到了他的拒绝。
- The tests for hepatitis were negative. 肝炎检查结果是阴性。