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- mdrl ribozyme mdrl核酶
- Ribozyme Any RNA molecule that acts as an enzyme. 核酶:任何可以起到酶的作用的RNA分子。
- The Relationship of Chinese Medicine Ganbikang and Ribozyme? 服用‘甘必康'能产生核酶吗?
- Ribozyme also known as type enzyme, the enzyme RNA, type of RNA. 核酶又称核酸类酶、酶RNA、类酶RNA。
- The results showed that the mdrl expression correlated with chemotherapeutic effect and prognosis. The mdrl expression was low in APL. 结果表明,mdrl的表达与患者化疗效果及预后密切相关,APL患者的mdrl为低表这。
- Objective To explore the role of calcium antagonist-isoptin on the cellular Mdrl product(P170) and apoptosis of ovarian carcinoma in chemotherapy. 目的探讨异博定对促进化疗药物诱使卵巢癌细胞增加凋亡因子表达的作用。
- After ribozyme action, the cell ratio of G0/G1 markedly increased, and the cell ratio of S phase markedly decreased. 核酶基因作用后,G0/G1期细胞比例明显增高,S期细胞比例明显降低;
- Objective: To confirm the cleavage activity of ribozyme Rz199 to oncogene K ras messenger RNA. 目的:确定人工设计的核酶Rz199对原癌基因K-rasmRNA的体外切割活性,为K-ras特异性核酶的体内应用提供依据。
- Ribozyme targeting cyclin Dl may effectively inhibit cyclin D1 expression and activation in the HSC T6 cell line. 载体表达的特异性核酶能有效地抑制HSC的细胞周期蛋白D1的表达和激活。
- The mdrl expression of 12 initial patients with APL was negtive, the complete remission (CR) rate was 100% (12/12). The mdrl was positive in 3 of 4 relapsed patients of APL (75%). 12例初治APL患者mdrl全部阴性,完全缓解(CR)率为100%25,4例复发ALP患者中3例mdrl阳性(75%25)。
- Methods Anti-NOX4 ribozyme clones of mouse embryonic stem (ES) cells were differentiated into embryoid bodies (EBs). 方法用核糖酶技术获得尼克酰胺腺嘌呤二核苷酸磷酸氧化酶4低表达小鼠胚胎干细胞克隆,将小鼠胚胎干细胞分化为胚小体。
- In vitro cleavage activity fo anti-Fas ribozyme was 60% and could decrease Fas expression on Yac-1 cells efficiently. 该核酶体外切割活性达6 0%25 ,且能有效降低细胞表面Fas的表达 ;
- The EGS can be covalently linked to Ml RNA, the catalytic RNA subunit of RNase P, forming a new kind of ribozyme, M1GS. 将EGS共价连接到M1 RNA的3′末端成为附属于M1 RNA的一段引导序列,称为GS。
- Ribozyme the substrate can be different elements, some substrate is the same RNA molecules in certain areas. 核酶的作用底物可以是不同的分子, 有些作用底物就是同一RNA分子中的某些部位。
- Intron removal is now thought to be an autocatalytic process in which the RNA acts as its own enzyme (see ribozyme). 目前认为内含子的切除是一个由RNA自身催化(参见ribozyme)的过程。
- Compared with the enzyme protein, low efficiency of the catalytic ribozyme, is a more primitive catalytic enzyme. 与蛋白质酶相比,核酶的催化效率较低,是一种较为原始的催化酶。
- Results The sequencing result showed that the third stem-loop of U1 was just replaced by the ribozyme sequences. 结果:经测序证实新建质粒中确实有核酶序列且替代了第3个茎-环。
- The new methods also include antisense nucleic acid technique and ribozyme technique in gene therapy... 新发展的还有反义疗法以及应用核酶进行基因治疗等。
- It is catalyzed by a complex of proteins and RNA molecules (a spliceosome), or sometimes by mRNA itself (see ribozyme). 这一反应由蛋白质复合物和RNA分子(剪接体)催化,或者由mRNA分子自身催化(参见ribozyme)。
- The molecular mechanism of different ribosomal ribozyme activeties to their selective inhibition by antibiotics. 内容介绍: A comprehensive resource considering virtually all aspects of ribosime structure and function.
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