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- Target compounds 4 and 5 were tested in a tubulin assembly assay,and in an in vitro cytotoxicity assay(KB cell line). 将目标化合物进行了抗肿瘤体外试验和微管聚合试验。
- It is active against Gram positive bacteria and has little inhibition on KB cells. 对革兰氏阳性菌有一定的抗菌活性
- Objective To study the relationship of cellular glutathione level in Pingyangmycin treated KB cells. 目的本研究探讨国产抗癌药平阳霉素作用培养肿瘤细胞时与胞内谷胱肽及其酶系统的关联性;
- To deplet the cellular glutathione level of KB cells ,the cytotoxicity of Pingyangmycin can be enhanced. 结果平阳霉素可通过谷胱甘肽及其酶系统失活;
- Results Treatment with Pingyangmycin resulted in a significant depletion of cellular glutathione levels in KB cells. 方法采用高效能液相层析仪分析法与MTT比色试验法进行检测。
- Oral epithelial carcinoma KB cell 口腔上皮癌细胞
- Some compounds exhibit cytotoxicity toward KB cells and P388 murine leukemia cells,and inhibitory activity against P-glycoprotein over expressing of adriamycin resistant cell line,K562/Adr cells. 一些成分在抑制KB细胞、P388白血病细胞和P-糖蛋白方面显示了较好的活性。
- By ELISA, McAb 3A5 and the Fab fragment were strongly reactive with hepatoma BEL-7402 cells and weakly reactive with KB cells. 在瘤、心、肝、脾、肺、肾、胃、肌、肠中,每克组织注射剂量百分比单抗3A5高于Fab片段,但肿瘤组织与非肿瘤组织的比值(T/NT)则Fab片段高于单抗3A5。 说明虽然完整单抗3A5在瘤组织的绝对浓度高于Fab片段,但是Fab片段分布特异性高于完整单抗3A5。
- Methods:The enhancement of chemosensitity of KB cells to vincristine(VCR) by dipyridamole in different concentrations was analysed with MTT method. 方法:使用MTT法检测比较KB母细胞和耐药细胞株对长春新碱(VCR)的药物敏感度并观察潘生丁对耐药的逆转程度;
- The endocytosis was efficient and rapid, as 97.5% KB cells cultured with folate-FITC-IO showed FITC uptake after 1 hour of incubation. 在将KB细胞与叶酸- FITC-IO纳米颗粒共培养1小时后;有97.;5%25的细胞被吞噬;说明细胞的内摄作用迅速且有效。
- The results showed that the levels of CMH and CDH in KBv 200 cells were higher than in KB cells, CMH was much more markedly increased, PPMP could reverse MDR by inhibiting CMH synthesis. 结果发现 ,KBv2 0 0 的CMH和CDH表达较KB强 ,尤以CMH为著 ,PPMP能抑制KBv2 0 0 细胞CMH的合成 ,并能逆转KBv2 0 0 对长春新碱 (VCR)的耐药性。
- McAb 3A_5, identified as IgGl, was directed against human hepatoma BEL--7402 cells. By ELISA, McAb 3A_5 and the Fab fragment were strongly reactive with hepatoma cells and weakly reactive with KB cells. 单抗3A_5和Fab片段分别与抗癌抗生素C1027偶联,偶联物经克隆生成法测定对肝癌细胞有很强的杀伤作用,C1027,Fab-C1027和3;
- Use of single-ligand formulations led to a reduction in viability (increased toxicity) not only in target KB cells but also in off-target cells with the targeted receptor available. 使用单配体配方不仅会导致靶向KB细胞活性的减少(增强了毒性),同时也使含有靶向受体的非靶向细胞活性降低。
- A storage cell in some amorphous memory devices. 某些非晶体存储器中的一个存储单元。
- She was found prostrate on the floor of the cell. 有人发现她趴在小屋的地板上。
- Antitumor activity of betulinic acid and its apoptotic on KB cell lines 桦木酸的抗肿瘤作用及其诱导KB细胞凋亡的研究
- The prisoner rapped out a message on the cell wall. 那囚犯敲打囚室的墙来传达讯息。
- The prisoner raped out a message on the cell wall. 那囚犯敲打囚室的墙来传达讯息。
- The growth of successive layers of a cell wall. 敷着,附着细胞壁连续层的生长
- The prisoner was locked in a cell. 那囚犯被关在单人牢房内。