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- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Objective To investigate the genetic polymorphisms of 15 STRs loci in Chinese Olunchun population. 目的调查15个STR基因座在中国鄂伦春族人群中的基因频率分布。
- In 1990 year, Willm and Welsh founded a new method in exploring genetic polymorph. 1990年’if! 。
- In this review,we provide an overview of human NER genetic polymorphisms as a predictive and prognostic marker in... 本文就核苷酸切除修复基因多态性和铂类药物耐药性关系研究进展作一综述。
- CYP2C9 gene has several mutant alleles leading to genetic polymorphisms in humans. CYP2C9基因具有遗传多态性,在人类存在几种等位基因的突变体。
- Objective To investigate the distribution of glutathione S transferase P1( GSTP1 ) genetic polymorphisms in cantonese of Guangdong province. 目的 了解谷胱甘肽 S 转移酶P1(GSTP1)基因多态性在广东省部分地区健康人群中的分布规律。
- Genetic polymorphisms of genomic DNA of 15 samples from wild and culturaled Gastrodia elata Blume in Guizhou were analyzed by RAPD method. 对贵州省境内药用植物天麻的野生和栽培15个样品的基因组DNA遗传多态性的RAPD分析。
- The genetic polymorphisms due to mutations in the methylene tetrahydrofolate reductase gene may increase the risk for NTDs. 亚甲基四氢叶酸还原酶基因突变导致的遗传多态现象可增加神经管缺陷(NTD)发生的危险性。
- The genetic polymorphisms of this locus in Yunnan Pumi population of China were studied.Two off-ladder alleles of DXS6804 locus were found. 结果调查了中国云南地区普米族人群基因座的基因型分布频率,发现DXS6804基因座两个分型标准物外等位基因。
- Methods Genotypes of HLA DM were determined by PCR RFLP.The relationship of HLA DM genetic polymorphisms with SLE was analysed by case control study. 方法用多聚酶链反应-限制性片断长度多态性(PCR-RFLP)确定DM的基因型,用病例对照研究的方法探索DM与SLE的关联性。
- Objective To study the relationship between genetic polymorphisms of glutathione s-transferase P1(GSTP1) and reflux esophagitis (RE). 目的探讨GSTP1基因型多态性表达与反流性食管炎的关系。
- Objective The genetic polymorphisms of CYP 1A1,CYP 2D6 and glutathione S?transferase M1 (GST M1) were analysed probed for the genetic markers of lung cancer. 目的探讨细胞色素P4501A1(CYP1A1),2D6(CYP2D6)和谷胱甘肽硫转移酶(GSTM1)基因多态性与肺癌易感性的关系。
- Objective To explore the association between genetic polymorphisms of glutathione S-transferase (GST) M1 and T1 and susceptibility to Kazak population esophageal cancer (EC). 目的 为探讨与致癌物代谢有关的谷胱甘肽转硫酶 (GST) T1和 M1基因多型性与哈萨克族食管癌易感性的关系。
- AIM To study the relationship between genetic polymorphisms of DCC gene STR in Shaanxi people and its possible association with the susceptibility of atherosclerosis. 目的 探讨 DCC基因 STR位点多态性与动脉粥样硬化遗传易感性之间的关系 .
- MTHFR C677T genetic polymorphisms were associated with individual susceptibility to esophageal cancer and hypermethylation rate of MGMT gene in the tumor tissues. 核苷酸切除修复基因XPC PAT和exon 15多态与食管癌遗传易感性间的联系较弱,叶酸代谢酶基因MTHFR C677T多态可能与食管癌遗传易感性和DNA异常甲基化有关。
- Objective To study the relationship between glutathione S-transferase(GST) M1/T1 genetic polymorphisms and the etiology and outcome of childhood acute lymphocytic leukemia(ALL). 目的研究谷胱甘肽S-转移酶(GST)M1/T1基因多态性与儿童急性淋巴细胞性白血病(ALL)易感性和预后的相关性。
- Objective To examine the relationship of genetic polymorphisms of glutathione S-transferase(GST) including GSTM1 and GSTT1 and the susceptibility to childhood leukemia. 探讨谷胱甘肽S转移酶M1(GSTM1)和T1(GSTT1)基因多态性与儿童白血病遗传易感性的关系。
- The genetic polymorphisms of drug-metabolizing enzymes,transporters or receptors play very important roles in the metabolism and therapeutical efficacy of oral antidiabetic drugs. 药物代谢酶、受体和转运体的遗传多态性对口服降糖药的体内代谢和降糖疗效有重要作用。
- OBJECTIVE To assess the influence of CYP2C9 genetic polymorphisms on warfarin dosage and anticoagulation effect in Chinese warfarin-treated patients of Han nationnality . 目的初步探讨入选的中国汉族服华法林患者CYP2C9*2和CYP2C9*3遗传多态性对华法林剂量和抗凝效果的影响。