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- Methods ACE gene polymorphisms of 47 stroke subjects with positive FHS and 145 subjects with negative FHS were identified by PCR. 方法采用聚合酶链反应技术（PCR）技术检测47例阳性FHS和145例阴性FHS脑卒中患者的ACE基因插入和缺失多态性。
- Study on the relationship between the RAS gene polymorphisms and renal impact in preeclampsia patients. RAS基因多态性与子痫前期肾脏损害的相关性研究
- TNF gene polymorphisms are related to many diseases including gastric cancer by influencing TNF production. 与包括胃癌在内的多种疾病的发生发展有关。
- H-FABP gene polymorphisms of Mashen pig and its offspring were detected by using the method of PCR-RFLP. 运用PCR-RFLP法检测马身猪及其杂交后代H-FABP基因多态性。
- Objective To determine the distribution of dopamine D2,D3, and D5 receptor(DRD2,DRD3,DRD5) gene polymorphisms in Guangzhou Hans. 目的 探讨广州地区汉族人群多巴胺 D2 (DRD2 )、D3(DRD3)、D5 (DRD5 )受体基因的多态性分布规律。
- The angiotensin (AGT) gene polymorphisms M235T and T174M are associated with mortality in heart failure (HF) patients, New Zealand researchers report. 新西兰科学家报道：他们发现血管紧张素（AGT）多基因型M235T和T174M与心力衰竭患者的死亡率有密切关系。
- The article reviews the structure and function of VDR, and its relafanship between gene polymorphisms and some diseases. 本文主要介绍了VDR的结构及功能、以及VDR基因多态性和与其相关的疾病。
- Objective To explore the relationship between gene polymorphisms of angiotensin converting enzyme(ACE) in the first wheezy children and wheeze relapas. 目的探讨首次喘息患儿血管紧张素转换酶(ACE)基因多态性表达及其与喘息再次发生的关系。
- Objective: To investigate the correlation between gene polymorphisms of HLA-DQB1 and rheumatoid arthritis (RA) in Ningxia Hui population. 摘要目的：探讨宁夏回族人群HLA-DQB1基因多态性与类风湿性关节炎(RA)的相关性。
- Objective To explore the significance of the gene polymorphisms of methylenetetrahydrofolate reductase(MTHFR)C677T in type 2 diabetes mellitus(DM)with coronary heart disease(CHD). 目的研究同型半胱氨酸代谢关键酶亚甲基四氢叶酸还原酶(methylenetetrahydrofolate reductase,MTHFR)基因C677T多态性与糖尿病合并冠心病发病的关系,探讨MTHFR是否为糖尿病合并冠心病的易感基因。
- Methods PCR was used to detect I/D gene polymorphisms of ACE in 149 children with asthma,108 children with wheezing pneumonia and 121 children with pneumonia. 方法对哮喘、喘憋性肺炎、肺炎三组的149、108、121例患儿,经PCR检测ACE基因I/D多态性分布;
- Recent epidemical study indicates that the incidence of AD in some populations is substantially influenced by the gene polymorphisms of the inflammation mediators. 近来流行病学研究显示炎症介质的基因多态性可以影响阿尔茨海默病在人群中的发病率。
- Method: The genotypes of FLAP gene polymorphisms are determined for each subject by polymerase chain reaction (PCR) amplification and denaturing HPLC, confirmed by sequencing. 方法：受试者之基因变异多形性以变性液态色层分析仪分型，并以去氧核糖核酸序列分析确认。
- Our aim was to examine the role of the sex hormone-binding globulin (SHBG) and androgen receptor (AR) gene polymorphisms, in the phenotypic expression of PCOS. 目的 研究性激素结合球蛋白（SHBG)和雄激素受体（AR）基因多态性在PCOS中的表型表达。
- Objective To evaluate the association of oral contraceptives (OC) use and angiotensin (ACE) gene polymorphisms on the risk of hypertension in Chinese women. 摘要目的评价口服避孕药(OC)的使用和血管紧张素转换酶基因(ACE)多态性联合作用对妇女高血压的发病风险。
- The latest advance of study for PPK is to analyze the effect on AEDs due to CYP450 gene polymorphisms, and to choose different initial doses according to gene polymorphisms. It will be valuable to facilitate individualized dosage regimen. 目前,已有研究将CYP450基因多态性的因素引入群体药代动力学的模型,将其对抗癫痫药物代谢的影响进行了量化,并且,可以依据不同的基因型选择不同的初始剂量,促进个体化治疗,取得了新的进展。
- The current advances of pharmacogenetics are discussed in this article,with an emphasis on the association between cytochrome P450(CYP2C19、CYP2D6、CYP1A1)gene polymorphisms and drug metabolisms. 本文介绍了药物遗传学的研究现状,并着重探讨三种细胞色素P450酶(CYP2C19、CYP2D6、CYP1A1)基因多态与药物代谢的关系。
- OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication. 目的:寻找丙戊酸药物浓度与CYP2C19基因多态性的关系,以便临床根据患者的基因型进行个体化给药。
- Methods:Gradient PCR was employed in analysis of aldosterone synthase(CYP11B2)gene polymorphisms,and gel Imaging Technology was used to determine the optimal annealing temperature. 方法:采用梯度PCR对醛固酮合酶基因(CYP11B2)进行扩增,通过凝胶呈像技术判断CYP11B2基因最佳退火温度。
- Analysis of the association of sulfonylurea receptor gene polymorphism with type 2 diabetes meilitus in Xinjiang. 磺脲类受体基因多态性与新疆地区2型糖尿病相关性研究。
