Objective To explore the significance of the gene polymorphisms of methylenetetrahydrofolate reductase(MTHFR)C677T in type 2 diabetes mellitus(DM)with coronary heart disease(CHD).

• 目的研究同型半胱氨酸代谢关键酶亚甲基四氢叶酸还原酶(methylenetetrahydrofolate reductase,MTHFR)基因C677T多态性与糖尿病合并冠心病发病的关系,探讨MTHFR是否为糖尿病合并冠心病的易感基因。