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- However,endothelin receptor antagonists could block those physiological action meditated by endothelin. 而内皮素受体拮抗剂却可阻断内皮素相应受体的生理学作用。
- The endothelin receptor antagonist bosentan is one of the effective drugs for pulmonary arterial hypertension. 内皮素受体拮抗剂波生坦是治疗肺动脉高压的有效药物之一。
- The physiological activities of endothelin,and development in endothelin receptor blocking agents were reviewed in this paper. 本文对内皮素和内皮素受体的生理活性及其受体阻断剂的发展进行了综述。
- Antagonist of endothelin receptor (ETA and ETB) could suppress the effect of ET 1 on inhibiting testosterone secretion,but Verapamile,a calcium channel blocker,could not do so. 内皮素受体A(ETA)、内皮素受体B(ETB)受体拮抗剂均可逆转ET 1对大鼠离体间质细胞睾酮分泌的抑制作用 ,但Ca2 +通道阻滞剂维拉帕米 (VER)未表现此作用。
- Objective To investigate the effect of endothelin receptor antagonist (BQ-123) on expression of matrix metalloproteinase-1(MMP-1) in rats with pulmonary fibrosis induced by bleomycin. 目的探讨内皮素受体拮抗剂BQ-123对肺纤维化大鼠基质金属蛋白酶-1表达的影响。
- The third, mRNA sequences of endothelin receptor A, B, C (ETA,ETB, ETC) of rats were analyzed and a 33 bp ETA probe was designed by "DNAstar" software, finally, ETA mRNA was analyzed by quantitative image analyzer. 用DNAstar软件包分析大鼠内皮素A、B、C受体(ETA、ETB、ETC)的mRNA序列，设计一33bp ETA探针；
- The author also discussed the methods of the animal model of the subarachnoid hemorrhage and the effect of endothelin receptor on the cerebral vasospasm caused by subarachnoid hemorrhage. 本文讨论了实验性蛛网膜下腔出血动物模型的制作方法，内皮素受体在蛛网膜下腔出血诱发脑血管痉挛中的作用。
- Vascular endothelial dysfunction has close relation ship with the development of pulmonary hypertension and prostacyclin analogue, endothelin receptor antagonists are new drug for the treatment. 血管内皮功能减退与肺动脉高压的发生发展具有极其密切的关系。前列环素类似物、内皮素受体拮抗药等是新开发的有效治疗肺动脉高压的药物。
- Through biological effect with the corresponding endothelin receptor，ETB receptor are mainly expressed by Ast in CNS ，therefore the astrocyte has been regarded as ET target cell. 在中枢神经系统，ETB受体主要在星形胶质细胞表达，因此可认为星形胶质细胞是ET的靶细胞。
- The endothelin system is composed of endothelins and endothelin receptors. 内皮素系统包括内皮素及其受体。
- Keywords Endothelin receptor Heart Radioligand binding assay; 内皮素受体;心脏;放射受体分析;
- A sensory receptor that detects warmth. 热探测器测量热量的敏感接受器
- The Potential of Endothelin Receptor Antagonists to be Novel Drug in Tumor Therapy 内皮素受体拮抗剂将成为肿瘤治疗中的新型药物
- Relationship between expression of hepatic endothelin receptor mRNA and portal pressure in cirrhotic rats 肝硬化大鼠肝脏内皮素受体基因的表达与门静脉压力的关系
- Changes of mRNA of endothelin receptor in kidneys of rats at the early stage after severe burns 严重烧伤早期大鼠肾脏内皮素受体mRNA变化的研究
- The Function of Endothelin Receptor AAntagonists BQ(123) Antagonizing Arrhythmia 内皮素A受体拮抗剂BQ_（123）抗内皮素的心律失常作用
- Keywords isopreterenol;sarco-endoplasmic reticulum ATPase 2a（SERCA2a）;endothelin receptor antagonist;CPU0213; 异丙肾上腺素;心肌细胞肌浆网钙ATP酶;内皮素受体拮抗剂;CPU0213;
- Endothelin receptor antagonist combined with a calcium channel blocker attenuates renal injury in spontaneous hypertensive rats with diabetes 内皮素受体阻断剂合用钙通道阻滞剂能抑制糖尿病高血压大鼠的肾脏损害
- The liver not only is the receptor of dietary fat. 肝脏是日粮脂肪的接受者。
- A Study on Combined Treatment with Endothelin Receptor Antagonist and Endothelium Derived Relaxing Factor in Rat Ischemic Acute Renal Failure 内皮素受体拮抗剂联合内皮源血管松弛因子防治大鼠缺血性急性肾衰竭
