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- It has linear double strand DNA,icosahedral-capsid and envelope. 其核酸结构为线状双股DNA,衣壳为二十面体对称,有囊膜。
- Like RNase A, the S-protein shows the samebehavior of shifting the melting temperature of double stranded DNA although it doesnot show any ribonuclease activity. 本文报道,核糖核酸酶A经枯草杆菌蛋白酶作用后,被切断而形成一个20肽和s-蛋白。
- In this experiment, DNA double strand breaks induced by heavy ions in the early period were investigated with atomic force microscopy (AFM). 本实验旨在用原子力显微镜(AFM)研究重离子辐射后早期的DNA双链断裂。
- The double strand probe was hybridized with DNA of liver, bone marrow, and spleen, stomach, small intestine, colon. and sera. PCR结果与双链探针的杂交结果一致,肝、骨髓、脾、胃、小肠和大肠组织及血清均阳性,都有TTV的感染。
- The NBS1 is a component of the MRE11/RAD50/NBS1 complex (MRN) and plays a critical role in the DNA double strand break (DSB) repair and the maintenance of chromosomal integrity. NBS1作为MRE11/RAD50/NBS1复合物的组分之一,是细胞应答DNA损伤的一个关键蛋白质,在DNA双链断裂修复和维持基因组稳定中发挥重要的作用。
- Immunohistochemical double staining showed that BrdU positive cells could costain with TUNEL, a marker of double strand DNA breaks, and 8-oxoG, an oxidative damage marker. 这提示BrdU+TUNEL双标细胞并不是新生神经元,这反应了缺血早期的BrdU掺入主要标记体内DNA的修复,且Bcl-2在缺血脑组织中的过表达可以影响体内的DNA修复能力。
- The effect of single and double strand breakage a nd itstransforming ac tivity of in vitro plasmid DNA was analysised by 30Kev N+、Ar+ ion beam radiatio n respectively. 利用30Kev的N+、Ar+离子辐照离体质粒DNA,分析了不同离子对DNA单双链断裂及转化活性的影响。
- Radiosensitization effect of 3-aminobenzamide( 3-AB), a specific inhibitor of ADP-ribose transferase( ADPRT), on cell colony formation and DNA double strand break (DSB), repair of human tumor cells was studied. 目的:从细胞的克隆形成能力和细胞DNA双链断裂及修复几方面探讨了ADP-核糖基转移酶(ADPRT)的特异性抑制剂3-氨基苯甲酰胺(3-AB)对人卵巢癌细胞株HOC8的放射增敏效应。 结果表明,3-AB能降低受照细胞的克隆形成能力;
- Using plasmid pGEM-3Zf(-) and M13mpl8 RF DNA, this thesis studied the DNA damage (DNA single strand break (SSB) and double strand break (DSB)), and gene mutation spectra induced by 30keV N+, C+ ions. 本文以质粒、噬菌体为实验材料,主要研究30keV的N~+、C~+引起的DNA分子损伤(单双链断裂)和它诱发基因突变的特点和规律。
- Objective To construct DNA double strand break(DSB) repair protein hKu70 deficient cell strain and to observe its biological characters for studying the functions of hKu 70 gene and the effects of occupational harmfulness factors on DSB repair. 目的 建立并鉴定DNA双链断裂 (DSB)修复蛋白hKu70缺陷细胞株 ,并观察该缺陷细胞的某些生物学效应 ,用于hKu70基因功能及职业有害因素对DNA双链断裂修复影响的研究。
- HR can repair the DNA double strand breaks (DSBs) which is the most severe damage of DNA. It is not known whether Hp induce the occurrence of GCa by inhibiting the functions of BER genes and HR genes? HR是真核细胞修复DNA双链断裂(DNA double strand breaks, DSBs)的一个重要途径, HR相关基因的缺陷可引起DSBs修复减少,肿瘤发生率显著增加。
- Pulsed field gel electrophoresis has been applied to compare the sensitivity of B16 cells and their DNA molecules in the induction of DNA double strand breaks (DSB) by 50 MeV/u 12 C 6+ beam. 用倒转脉冲场凝胶电泳 (PIGE)比较研究了 50 Me V/u1 2 C6 +辐照小鼠 B1 6黑色素瘤细胞及其脱蛋白 DNA分子 ,从而诱导 DNA双链断裂 (DSB)的辐射敏感性。
- The results showed that the residual double strand DNA percentages (dsDNA%) in dune reed (DR) were significantly higher than those in swamp reed (SR) treated with either 20% or 30% PEG 6000. 结果表明:无论是20%25还是30%25PEG6000胁迫处理,耐旱性强的沙丘芦苇的DNA损伤都比耐旱性弱的沼泽芦苇较轻。
- Interferon is human body gets virus or double stranded the exciting generation immunity of RNA exciter is respondent, by the cell synthesis reachs excretive gens protein kind. 干扰素是人体受到病毒或双股RNA刺激物的刺激产生免疫应答,由细胞合成及分泌的一族蛋白质类。
- histone-free double stranded DNA 无组蛋白双链DNA
- antibodies to double stranded DNA 双螺旋脱氧核糖核酸抗体
- anti - double stranded DNA antibody ( anti - dsDNA) 抗双链DNA抗体
- Double stranded anti DNA antibody 双股抗DNA抗体
- The cytoplasmic polyhedrosis virus of the silkworm is the prototype of a large group of animal, plant, fungal and bacterial viruses that contain segmented double stranded RNA. 以双链核糖核酸为基因组的病毒寄主范围很广,如哺乳动物的呼肠病毒,昆虫的细胞质多角体病毒,植物的水稻矮缩病毒,以及某些微生物的病毒,已经发现有十余种之多。
- The results showed that BK chromosomes reveal a multiple double strand helical structure . 观察到BK染色体具有多级双股螺旋结构。