Immunohistochemical double staining showed that BrdU positive cells could costain with TUNEL, a marker of double strand DNA breaks, and 8-oxoG, an oxidative damage marker.

• 这提示BrdU+TUNEL双标细胞并不是新生神经元，这反应了缺血早期的BrdU掺入主要标记体内DNA的修复，且Bcl-2在缺血脑组织中的过表达可以影响体内的DNA修复能力。