- Objective In order to search for new tumor differentiation inducer, the effects of matrine of Chinese herbal origin on differentiation of K562 cells and its mechanism were studied.
- By derived differentiation,we mean that under the effect of differentiation inducer,malignant tumor cell has the tendency to differentiate to normal cell,even became normal cells.
- TATS has a differentiation inducing effect on untreated and recurrent APL, with haematological CR and cytogenetic CR achieved.
- The establishment of the gene expression profile and cloning the genes associated with differentiation inducing of human glioma cells.
- The telomerase gene associated with other genes would be an important regulated target in the differentiation induced by retinoids.
- Keywords Chordoma;Cell line;differentiation inducer;invasion;