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- Codon usage bias varies considerably among genomes and even within the genes of the same genome. 密码子使用偏好性在不同的基因组中甚至在同一个基因组中的不同基因中都是不同的。
- Thus, codon usage bias of nuclear genes appeared to be affected by translational selection. 因此，核基因的密码子使用偏好性受到翻译选择的影响。
- The results of codon usage bias analysis did not support that MscL-like progenitor is the common ancestor of MSC. 密码子使用偏性的分析结果不支持MscL 样分子是MSC 的进化原型。
- As gene type and function is fixed, species difference can also affect codon usage bias.The closer the consanguinity between species in evolution, the similar their codon usage bias is. 在基因的类型和功能一定的情况下，物种的差异也会影响到密码子的使用偏性，在进化上亲缘关系较近的物种间，其相对密码子使用概率也较接近。
Codon usage bias varies considerably among genomes and even within the genes of the same genome.
密码子使用偏好性在不同的基因组中甚至在同一个基因组中的不同基因中都是不同的。- Some genes are G+C rich, some others are A+T rich, while the rest do not show obvious nucleotide bias. (2) codon usage bias varies considerably among the MSC genes; 部分基因呈G+C 丰富，部分基因呈A+T 丰富，而另有一部分基因无明显的核苷酸组成偏性；
- Codon usage bias 密码子偏好性
- Keywords rice;chloroplast;mitochondrion;codon usage bias;gene function;translation initiation codon;translation termination codon;sequence pattern;gene expression level;readthrough gene; 水稻;叶绿体;线粒体;密码子偏好性;基因功能;起始密码子;终止密码子;侧翼序列模式;基因表达水平;通读基因;
- We optimized the codon usage of wild type HPV 16 L1 gene according to the codon bias of mammalian,and synthesized the full-length optimized L1 gene,named mod. 首先按照哺乳动物密码子偏好对野生型HPV16 L1基因进行改造并合成优化基因;命名为mod.;HPV16L1。
- As a result , a codon usage clock was reported in apolipoprotein A-I. 结果显示:载脂蛋白分子演化中存在着同义密码子使用的分子进化钟。
- Correspondence analysis has frequently been used for codon usage studies. 对应分析法在密码子用法的研究中频繁使用。
- The codon usage patterns were phylogenetically conserved among these Crenarchaeota microorganisms. 这3种泉古菌的密码子使用模式在进化上很保守。
- The Factors Shaping Synonymous Codon Usage in the Genome of Burkholderia mallei. Sheng Zhao，Qin Zhang，Zhihua Chen，Yixin Zhao， Jincheng Zhong (通讯作者).
- Although factors affecting codon usage in a single genome have been studied, this has not occurred when both interactional ge-nomes are involved. 尽管同一个基因组的密码子使用偏好性已经得到了广泛研究，但是相互作用的两个基因组间的密码子使用偏好性还未见报道。
- Moreover, species with near homology relationship on evolution share the near codon usage frequency and preference index or the similar index. 在同源性方面，在进化上比较接近的物种，基因的密码子使用频率和使用偏性指标比较接近或基本相同。
- In other words, gene function and type determines the main classification of codon usage, while species determines further differences in a class. 研究表明：基因的功能和类型决定密码子使用模式的大的分类，而物种决定了在该大类基础上进一步的差异。
- Comparatively, it is the species function rather than the gene function that determines their gene codon usage patterns. 与基因的功能对密码子使用的影响相比，这些泉古菌密码子的使用偏向性更是由其物种所决定的。
- Furthermore, the earlier the species differentiation time on evolution, the lower the difference of the codon usage frequency and preference and the higher by contraries. 在进化上分化时间越早的物种，密码子使用频率和使用偏性的差异较小，反之则较大；
- As a result, codon is an important study field in modern molecular genetics and bioinformatics.Because of the degeneracy of genetic codes, synonymous codon usage is biased. 对于密码子的研究，长期以来一直是分子遗传学以及生物信息学的研究重点。
- Knowledge of codon usage in prokaryotic mechanosensation genes may benefit for the study in eukaryotes in which only few of them have been identified and functionally analysed. 真核生物中至今仅有少数几个机械敏感性离子通道（mechanosensitive ion channel，MSC）基因被发现，对原核生物MSC 基因的密码子使用进行研究，希望能为真核生物MSC 的研究提供有意义的线索。
