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- Chitosan nanoparticle has co-permeation and bioadhension,which has a wide development in the research of gene delivery system. 用壳聚糖制备的纳米粒具有助渗作用及生物粘附性,在基因递送载体的研究中具有广阔的发展前景。
- Galactosylated chitosan nanoparticle was prepared by the cross-linking of sodium tripolyphosphate and galactosylated chitosan. 通过离子交联剂三聚磷酸钠与半乳糖基壳聚糖的氨基之间发生交联作用制备得到半乳糖基壳聚糖纳米粒子。
- When the chitosan nanoparticles loaded insulin (INS),the pharmacodynamics after pulmonary administration in vivo was evaluted. 以胰岛素(Insulin,INS)为模型药物,建立药物含量测定方法,通过呼吸道插入给药,进行胰岛素壳聚糖纳米粒的体内初步药效学研究。
- Aim:To prepare and characterize the adriamycin-loaded chitosan nanoparticles of the surface-modified with glycyrrhizin (GL-ADM-CS-NPs). 目的:制备具有肝细胞靶向的甘草酸表面修饰阿霉素壳聚糖纳米粒,并考察其理化特性。
- Abstract:Objective To prepare folate??conjugated 5??fluorouracil??chitosan nanoparticles (5??FU??CSNP??folate) and evaluate its property in vitro. 目的研究叶酸偶联壳聚糖载5?卜?尿嘧啶纳米粒的制备方法及体外性质。
- Methods:Prostate cancer cells PC-3 and 22Rvl were transfect- ed with plasmid pEGFP-C1 coated with chitosan nanoparticles and the expression of EGFP was observed. 方法:将壳聚糖纳米粒包裹的含报告基因的质粒pEGFP-C1分别转染前列腺癌细胞PC-3和22Rv1,并观察EGFP的表达情况。
- Conclusion: chitosan nanoparticles can deliver gene into cell and express in these celles.Immunity test proved that it has favourable immunological enhancement. 结论: 壳聚糖纳米粒能将基因递送到细胞内并且能够表达,小鼠免疫实验显示其具有良好的免疫增强效果。
- To study the liver targeting trend of all kinds of norcantharidin chitosan nanoparticles(NCD-NP) in mice in order to discuss the influence of targeting of different parameters of CS. 研究不同去甲斑蝥素壳聚糖纳米粒在小鼠体内的肝靶向性,以判断壳聚糖分子参数对其肝靶向性影响。
- magnetic chitosan nanoparticles(MCNP) 磁性壳聚糖微球(MCNP)
- folate-conjugated chitosan nanoparticles 叶酸偶联壳聚糖纳米粒
- chitosan nanoparticle 壳聚糖纳米颗粒
- Preparation of silicon oxide nanoparticle. 纳米二氧化硅粉体的制备。
- AUC of nanoparticle was 25.8 times of injection. AUC是注射剂的25 .;8倍。 而PEG化壳聚糖修饰的
- Preparation and characterization of magnetic chitosan nanoparticles 磁性壳聚糖纳米粒子的制备及表征
- Study on Release of Resveratrol from Chitosan Nanoparticles 白藜芦醇壳聚糖纳米粒体外释放行为研究
- Study on the immunoregulation of chitosan in mouse. 壳聚糖免疫调节作用的研究。
- Their cell walls contain chitin or chitosan. 它们的细胞壁含有角素或壳聚糖。
- Preparation and Characterization of Folate-coupled Chitosan Nanoparticles 叶酸偶联壳聚糖纳米粒的制备
- PRELIMINARY STUDY OF CHITOSAN NANOPARTICLES USED AS GENE DELIVERY CARRIERS 壳聚糖纳米粒用作基因递送载体的初步研究
- The entrapping of ADM in ADM-loaded nanoparticle(ADMNP)is 0.78mg/ml. 纳米粒阿霉素的载药量为0.;78mg/ml;