When the chitosan nanoparticles loaded insulin (INS),the pharmacodynamics after pulmonary administration in vivo was evaluted.

• 以胰岛素(Insulin，INS)为模型药物，建立药物含量测定方法，通过呼吸道插入给药，进行胰岛素壳聚糖纳米粒的体内初步药效学研究。