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- AIM:To investigate the expression of CC chemokine receptor 7 (CCR7) in different types of lung carcinoma and its clinical significance. 目的:探讨趋化因子受体CCR7在不同类型肺癌组织中的表达及其临床意义。
- CC chemokine receptor 7 CCR7
- Chemokine receptor 7 CCR7
- The chemokine receptor CXCR6 and its ligand CXCL16 are involved in inflammation. 趋化因子受体CXCR6 及其配体CXCL16的作用是参与炎症。
- The molecular evolutionary rates of chemokine receptor genes are different, with CXCR4 gene scored the lowest. 趋化因子受体的进化速率不同,其中CXCR4的进化速率最低。
- Abstract: Objective To explore the correlation between structure domains and function of chemokine receptor CXCR4. 摘 要: 目的 认识趋化因子受体CXCR4之结构与功能的关系。
- The aim of this article is to review recent devel-opment of CCR7,a newly identified chemokine receptor,and its ligand CCL21and CCL19. 全文就新近发现的趋化因子受体CCR7及其配体CCL21和CCL19的研究进展作一综述。
- Neuropeptide B(NPB) that consists of 29 amino acid was identified to be an endogenous ligand for the G-protein coupled receptor 7 (GPR7). 神经肽B是一个由29个氨基酸组成的肽,它是G-蛋白耦联受体7(GPR7)的内源性配体,它们在中枢神经系统有广泛的表达。
- Objective To investigate whether homocysteine (HCY) can induce the expression of chemokine receptor CCR1 mRNA in cultured THP-1 monocytes. 目的 探讨同型半胱氨酸对人单核细胞株THP 1表达趋化因子受体CCR1mRNA的影响。
- Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). 目的研究细胞趋化因子受体5(CCR5)在乙型病毒性肝炎(HB)免疫发病机制中的作用。
- Chemokine CCL21 is a ligand of chemokine receptor (CCR)7. It is constitutively expressed at high level in secondary lymphoid organs (thymus, lymph node, spleen). 趋化因子CCL21是趋化因子受体(CCR)7的一个配体。 它在次级淋巴器官(胸腺、淋巴结、脾脏)中组成性高表达。
- Objective To explore the relationship between chemokine receptor CCR5, CCR2 gene polymorphism and Chinese type 1 diabetics, as well as their first relatives. 目的 探讨趋化因子受体CCR2、CCR5基因多态性与 1型糖尿病 (T1DM)及其一级亲属之间的关系 ,并与T2DM及非DM对照进行比较。
- Thymus and activation -regulated chemokine (TARC) , a CC chemokine, was identified as a selective chemoattractant for CC chemokine receptor 4 (CCR4) - expressing cells to ti-uss. 胸腺和活化调节趋化因子(thymus and activation-regulated chemokine,TARC)是CC型趋化因子,其受体是CC趋化因子受体4(CC chemokine receptor 4,CCR4),在活化的Th2细胞上呈优势表达,它们共同作用使Th2细胞由血液迁移到一定的组织中。
- To investigate the expression of chemokine receptor CCR7 in peripheral lymphocytes of gastric carcinoma and its relationship with clinicopathological characteristics. 目的研究趋化因子受体CCR7在胃癌患者外周血淋巴细胞各亚群的表达,并与健康人进行比较,探讨其与临床病理分期之间的相关性。
- This review focuses on recent advances in understanding the CD4+ CD25+ regulatory T cells, chemokine and receptor, chemokine receptor expressing on CD4+ CD25+ Tr cells and the attraction of these cells by antigen presenting cells (APCs). 了解CD4+CD25+Tr细胞、趋化性细胞因子、趋化性细胞因子受体和表达于CD4+CD25+Tr细胞上的趋化性细胞因子受体以及它们与不同的抗原提呈细胞(APCs)之间的作用的最新研究进展十分必要。
- To explore the role of the autoantibodies(GADA,IAA,ICA), the polymorphisms of chemokine receptor CCR5 , CCR2 , and the expression of CD4+CCR5+ and CD4+CCR3+ in the PBMC of the type 1 diabetes mellitus in prediction and diagnosis type 1 diabetes. 检测1型糖尿病患者的血清自身抗体水平、趋化因子受体CCR5、CCR2的基因多态性,以及趋化因子受体CCR5、ECR3在1型糖尿病患者外周血CD4~+T淋巴细胞中的表达水平,研究这些检测指标对1型糖尿病早期预报和早期诊断的意义。
- Toll-like receptor 7 (TLR7) gene Toll样受体7(TLR7)基因
- nicotinic acetylcholine receptor α7 烟碱样乙酰胆碱受体α7
- The chemokine receptor CCR5 is implicated in the pathogenesis of various inflammatory diseases, such as multiple sclerosis (MS), atherosclerosis, transplant rejection, and autoimmunity. CCR5与多种炎症性疾病的发生密切相关,如多发性硬化症,动脉粥样硬化,移植排斥,自身免疫等。
- Objective To investigate different significance and expression of the CC chemokine receptor CCR7 of T cells from the peripheral blood or skin models in patients with psoriasis vulgaris. 目的探讨趋化因子受体家族中CC趋化因子受体7(CCR7)在寻常型银屑病患者皮损及外周血T细胞上的表达情况。