a fundamental alteration

• 根本的改变

a fundamental alteration的用法和样例：

例句

1. Now that fundamental changes have taken place in our country's political situation,fundamental changes have to be made in our current political programme accordingly.
   我国的政治情况既然发生了根本的变化，我们在目前时期的政治纲领，当然也要有根本的改变。