Vascular Endothelial Growth Factor and its receptors may be the pivotal stimulants in the process of growth and metastasis of a neoplasm. 血管内皮生长因子及其受体在肿瘤的生长和转移过程中可能是最关键的刺激因子。
Beacizumab, a monoclonal antibody targeting ascular endothelial growth factor, is approed by the US Food and Drug Administration for metastatic colon cancer. 由美国食品与药品管理局批准治疗转移克隆癌的贝伐单抗,是血管内皮生长因子的单克隆抗体。