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- Smyth MJ,Krasovskis E,Sutton VR,et al.The drug efflux Pro tein,P-glyoprotein,additiionally protects drug-Resistant tumor cells from multiple forms of caspase-dependenl apoptosis[J].Proc Natl Acad sci USA,1998,95:7024. 阚兵;罗锋;雷松;等.;用流式细胞术检测肿瘤组织细胞多药耐药基因表达产物[J]
- A study of tumor suppressor genes on chromosome 9 in glioblastomas. 胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
- BRCA1 inactivates a tumor suppressor gene known as PTEN. BRCA1能够使人体内一种叫PTEN的肿瘤抑制基因失去活性。
- Endogenous angiogenesis inhibitors act as tumor suppressor proteins. 内源性血管生成抑制剂可作为一种抑癌蛋白。
- As an osteocarcinoma-associated antigen,bone morphogenetic pro tein(BMP) is of significant in the clinical study of osteocarcinoma. 骨形成蛋白(BMP)作为一种骨肿瘤的相关抗原,在骨肿瘤的临床医学研究中具有重要意义。
- Androgen Receptor in liver cancer progression. Oncogene or tumor suppressor? 男性激素受体与肝癌:致癌或是抑癌基因?
- The advances in the study of tumor suppressor genes in gliomas were reviewed. 作者就目前在脑胶质瘤中研究较多的抑癌基因的进展作了综述。
- Hamaker B.R.and Griffin V.K.,Effect of disulfide bond-containing pro tein on rice starch gelatininzation and pasting.Cereal Chen. 邱明发、金铁成、周瑞芳;等.;米谷蛋白与淀粉组分在大米陈化过程中的变化
- In contrast, undifferentiated carcinomas rarely exhibit structurally altered tumor suppressor genes. 相反,未分化癌极少表现出抑癌基因结构的改变。
- Recent evidence suggests that Tob could be a tumor suppressor gene in lung cancer. 最近的研究表明:在肺癌的发病机制中Tob可能为抑癌基因。
- In 4 0 cases of hepatocellular carcinoma (HCC), 6 cases were positive for bcl-2 pro tein staining (15%). Bcl-2 gene breakpoints were found in 8 cases (20%), 4 case s in mbr site and 4 cases in mcr site. 40例肝细胞肝癌中 6例bcl 2蛋白阳性 ,阳性率为 15%25 ,发生bcl 2基因断裂有 8例 ,阳性率为 2 0%25 ,mbr和mcr阳性各 4例 ;
- Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array. 目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
- The NF1 tumor suppressor encodes a protein product neurofibromin,which functions as a negative regulator of RAS. NF1为肿瘤抑制基因,是RAS的负向调节器。
- Objective To investigate the expression of tumor suppressor gene PTEN in breast carcinomas and its significance. 摘要目的研究肿瘤抑制基因PTEN在乳腺癌组织中的表达及临床意义。
- CONCLUSION: RUNX3 gene may be one of the important candidate tumor suppressor genes in carcinogenesis of GC. 结论: RUNX3 可能是胃癌发生中重要的候选抑癌基因。
- The list of cancer-related mutations has grown to more than 100 oncogenes and 15 tumor suppressor genes. 与癌症有关的突变基因名单上,致癌基因已经增加到超过100个,而肿瘤抑制基因也有15个。
- Objective To investigate expression and significance of tumor suppressor gene PTEN in esophageal carcinoma. 目的探讨抑癌基因PTEN在食管癌中的表达及临床意义。
- We demonstrate that Chd5 functions as a tumor suppressor in io and implicate deletion of CHD5 in human cancer. 我们证明Chd5在活体中作为抑癌基因发挥作用而且在人类恶性肿瘤与CHD5的缺失有关。
- The expression of genes that inhibit cancer deelopment, so-called tumor suppressor genes, is often lost in tumor cells. 抑制癌症发生的基因即所谓的肿瘤抑制基因,其表达常在肿瘤细胞中缺失。
- Rb correlates with tumorigenesis closely, and is an important tumor suppressor gene. Rb与人类多种肿瘤发生关系密切,是一种重要的肿瘤抑制基因.