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- Tumor suppression gene PTEN 抑癌基因PTEN
- Its anti tumor effect exhibits cell proliferation suppression, appoptosis induction, cell signal disturbing, tumor suppression gene activity enhancing and oncogene expression suppression etc. 其抗肿瘤作用主要表现在抗细胞增殖、诱导细胞凋亡、干预细胞信号转导和增强抑癌基因活性及抑制癌基因表达等功效。
- The paper reviews the outcomes and developments of scientific experiments on oncogene and tumor suppression genes about human glioma. 本文试综述与胶质瘤相关的癌基因与抑癌基因的研究成果与进展。
- Wang XJ, Zeng FF, Xu ZW, et al: Detection of tumor suppressive gene and oncogene in SO-Rb50. Human retinoblastoma cell line. Eye Science 1993; 9: 34. 冯官光;李永平;易玉珍;等:视网膜母细胞瘤细胞系裸小鼠异体移植瘤实验研究.;中华眼科杂志1994;30:47
- Keywords epigenetics;methylation;gastric carcinoma;tumor suppress gene; 关键词表观遗传学;甲基化;胃癌;抑癌基因;
- Keywords prostate cancer;Immunohistochemistry;PTEN protein;tumor suppresser Gene;P-ERK; 关键词前列腺癌;免疫组织化学;PTEN蛋白;抑癌基因;P-ERK;
- While tumor suppressing genes p53 and WT1 present negative roles in hTERT expression, including other negative regulators: MZF-2 and Mad. 另外，p53、WT1、MZF-2和Mad是已知的对hTERT的转录起抑制作用的因子。
- multiple tumor suppresser gene 1 多种瘤抑制基因, 即P16基因, 位于9q21, 系抑癌基因
- Expression of Tumor Suppress Gene DLC-1 in the Colorectal Cancer Cell Line Sw480 抑癌基因DLC-1在结肠癌细胞sw480中表达的研究
- Keywords tumor suppression gene;eukaryote expression vector;recombinant plasmid; 肿瘤抑制基因;真核表达载体;重组质粒;
- It was found that wild-type gene PTEN could suppress the proliferation of hepatocellular carcinoma cells and induce G1 phase block wile the mutated PTEN gene lost this function. 本课题最后发现野生型PTEN基因可抑制肝癌细胞的增殖，诱导G1期阻滞；而突变的PTEN基因无上述作用。
- CONCLUSION:PTEN may suppress tumor cells growth,the result makes the base for further study on the tumor suppression fumction of PTEN. 结论：PTEN可能能抑制肿瘤细胞生长，为后进一步开展PTEN对肿瘤相关功能的研究奠定基础。
- Objective To investigate the expression of tumor suppressor gene PTEN in breast carcinomas and its significance. 摘要目的研究肿瘤抑制基因PTEN在乳腺癌组织中的表达及临床意义。
- Objective To investigate expression and significance of tumor suppressor gene PTEN in esophageal carcinoma. 目的探讨抑癌基因PTEN在食管癌中的表达及临床意义。
- Objective To detect the expression of a novo tumor suppressor gene PTEN and DNA direct repair enzyme MGMT in gynecomastia. 目的观察抑癌基因PTEN和DNA直接修复酶MGMT在男性乳房发育症(GM)乳腺中的表达。
- Objective To investigate the expression and significance of tumor suppressor gene PTEN and oncogenes Ki- ras in endometrioid endometrial adenocarcinoma(EEC). 目的探讨PTEN基因、Ki-ras基因在子宫内膜腺癌中的表达及意义。
- Keywords Fragile histidine triad gene;Tumor suppression genes;Laryngeal neoplasms; 脆性组氨酸三联体基因;抑癌基因;喉癌;
- Conclusion The abnormal expression of tumor suppressor gene PTEN and MGMT in gynecomastia probably plays an important role in the development of gynecomastia. 结论GM乳腺组织中PTEN与MGMT表达的异常可能与GM的发生有关。
- Wilms tumor suppression gene Wilms瘤抑癌基因
- Tumor suppress gene 肿瘤抑制基因
