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- Objective To investigate the function of CD4~ + CD25~ + T regulatory cells(Tr) in allogeneic lymphocyte therapy of unexplained recurrent spontaneous abortion(URSA) patients. 目的探讨CD4+CD25+调节性T细胞(Tr)在原因不明复发性流产(URSA)患者主动免疫治疗中的作用。
- Methods Peripheral blood mononuclear cells(PBMCs) were stained by monovlonsl antibody,and changed proportion of CD4+CD25+FOXP3+ T regulate cells were determined by Flow cytometer. 方法用荧光标记的单克隆抗体染色外周血单个核细胞,利用流式细胞仪检测CD4+CD25+FOXP3+调节性T淋巴细胞的改变。
- T regulatory cells 调节性T细胞
- T regulatory cell T调节淋巴细胞
- immunological T regulator cells 免疫调节性T细胞
- The CD4~+ CD25~+ Tr regulatory cells,a subpopulation of T cells,have specific immuno regulation function,which may be one of the mechanisms which can induce spontaneous im- mune tolerance following rat liver transplantation. CD4~+CD25~+Tr细胞是一种具有特异免疫调节功能的T细胞亚群,其主动的免疫抑制功能可能是诱导大鼠肝移植自发免疫耐受的机制之一。
- The feeding of low antigen doses leads to induction of regulatory cell secretion of immunosuppressive cytokines,whereas higher doses favor clonal deletion and anergy. 低剂量口服抗原主要通过调节性T细胞分泌抑制性细胞因子介导免疫抑制,高剂量口服抗原主要引起T细胞清除或T细胞失能。
- antitheta sensitive regulatory cell 抗O敏感性调节细胞
- Proliferating cell nu clear antigen (PCNA) plays a vital role in regulating cell replication, repair, and death, and is found in an altered form in breast cancer cells. 增殖细胞核抗原在细胞应答、修复及死亡的调控中起着重要作用,并被发现其在乳癌细胞中出现形态改变。
- They all regulate cell cycle and apoptosis, but their bi ological effects are adverse. 虽然两者均参与细胞周期调控和细胞凋亡,但两者生物学效应却是相反的。
- Voltage-gated potassium channels regulate cell membrane potential and excitability in neurons. 电压门控性钾通道维持神经元静息膜电位,参与细胞兴奋性的改变。
- IGFs take in part in regulating cell generation, which is produced by liver and resided in blood. 该类调节因子主要由肝脏产生,存在于血液中,参与调节细胞的生长增殖。
- Insulin-like growth factor (IGF) system plays an important role in regulating cell proliferation and differentiation, and inhibiting apoptosis. 胰岛素样生长因子系统在调节细胞增殖、分化与抑制凋亡中发挥重要作用。
- FTY was additive with regulatory T cells for GVHD inhibition. FTY与调节性T细胞联合抑制了GVHD。
- The plant phytohormone cytokinin regulates numerous growth and developmental processes by regulating cell division and cell differentiation. 作者单位:中国科学院遗传与发育生物学研究所植物基因组学国家重点实验室;
- Abstract The plant phytohormone cytokinin regulates numerous growth and developmental processes by regulating cell division and cell differentiation. 摘要 在高等植物中, 细胞分裂素通过对细胞分裂与分化的调节而广泛参与了对植物生长发育的调控。
- In recent years,it has been reported that CsA can regulate cell apoptosis.This paper reviewed the effects of cyclosporin A on cell apoptosis. 近年来文献报道环孢菌素A对细胞凋亡有一定的调节作用。
- WNT signaling has been identified as one of the key signaling pathways in cancer, regulating cell growth, motility and differentiation. 摘要WNT信号通路在肿瘤发生中有重要意义,它调节细胞生长、迁移和分化。
- Caspase family is the critical elements in PCD.They regulate cell death or survival by interaction with many proteins(activators or inhibitors). Caspase家族是整个PCD过程的关键元件,它们通过与众多蛋白质(激活因子或抑制因子)的相互作用来调控细胞的生死存亡.
- P 27Klpl is a kind of cyclin dependnt kinase inhibitor (CKI) and it can regulate cell cycle through restraining cyclin and cyclin dependnt kinase (CDK). _p27蛋白是一种细胞周期蛋白依赖性激酶抑制剂(cyclin dependnt助兴大尝医笋朦硕生~研羌生.;早业讼戈