The CD4~+ CD25~+ Tr regulatory cells,a subpopulation of T cells,have specific immuno regulation function,which may be one of the mechanisms which can induce spontaneous im- mune tolerance following rat liver transplantation.

• CD4~+CD25~+Tr细胞是一种具有特异免疫调节功能的T细胞亚群,其主动的免疫抑制功能可能是诱导大鼠肝移植自发免疫耐受的机制之一。