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- Keywords Swellable matrix tablet;Release mechanism;Modeling;Swelling;Erosion;Diffusion;Front movement; 溶胀型骨架片;释药机制;模型;溶胀;溶蚀;扩散;前沿移动;
- Swellable matrix tablet 溶胀型骨架片
- METHODS To establish a HPLC method for determing the content of ribavirin.The water-soluble matrix tablet was preparaed by use of HPMC.The optimal formulation was obtained by uniform design. 方法:建立高效液相色谱(HPLC)体外释放度测定法,以羟丙基甲基纤维素(HPMC)为主要辅料,制备亲水凝胶型骨架片,采用单因素试验筛选辅料种类,通过均匀设计优化出缓释片的处方。
- Aim The water-soluble matrix tablets were prepared b y using of HPMC (K4M) . 目的:以HPMC为主要材料，制备水溶性骨架片。
- Objective:To prepare the mixed matrix tablets of Loxoprofen sodium and to evaluate their dissolution in vitro. 目的:制备洛索洛芬钠混合性缓释片并考察其体外释放度。
- Xanthan gum hydrophilic matrix tablets were prepared using theophylline as a model drug. 以茶碱为模型药物，制备了黄原胶亲水性骨架片，研究了体外释药的影响因素。
- Objective To study the release kinetics of theophylline from the hydroxypropyl methylcellulose (HPMC) matrix tablets in vitro release test. 目的研究以羟丙基甲基纤维素(HPMC)为基材的茶碱片剂在体外溶出的动力学规律。
- Objective To investigate factors influencing the in vitro release of sulindac from the hydrogel matrix tablets and optimize the formulation. 目的 研究舒林酸亲水凝胶缓释骨架片体外释放的影响因素，筛选最优处方。
- AIM To investigate the affecting factor of the diclofenac potassium release in vitro from hydroxypopylmethylecellulose(HPMC) matrix tablets. 目的考察影响双氯芬酸钾羟丙基甲基纤维素(HPMC)骨架片体外释放的各种因素。
- OBJECTIVE:To make diclofenac sodium(DCF) hydrophilic matrix tablets and examine the factors affecting their dissolution rates. 目的：制备双氯芬酸钠（DCF）亲水凝胶骨架片，并对其释药影响因素进行了研究。
- This kind of tablet is soluble in water. 这种药片能溶于水。
- The HPMC matrix tablets of Urpaidil were prepared by the wetmethod,using hydroxypropylmethylcellulose(HPMC)as the matrix material. 以HPMC为骨架材料，采用湿法制粒，制备了乌拉地尔缓释片。
- Aspirin controlled release matrix tablets were prepared using quantitative controlling method of high speed stirring granulation technology. 用均匀设计法设计试验，对高速搅拌制粒工艺进行定量化控制，制备了阿司匹林控释骨架片。
- RESULTS:Formulation 7 had good slow releasing rate.The stabili ty test results showed that the matrix tablets were stable under the test condit ions. 结果：处方7具有很好的缓释效果，稳定性研究表明该缓释片的稳定性良好。
- There is a tablet in memory of those who died. 那儿有一块碑纪念死去的人。
- The extensions of dissolution of tranilast from the SR matrix tablets,to their perfect extent were 0.72%(in SGF),94.3%(in SIF) and 98.7%(in gradient pH) within 10 hours. 相同条件下 ;曲尼司特缓释片在人工胃液、人工肠液和梯度pH溶液中 ;10h的释放度分别为 0 .;72%25、94
- Results as follows: In the HPMC matrix tablets, we studied the effect of the content and the viscosity of HPMC, particle size of MNZ, shape and weight of ta. 结果如下:以HPMC为辅料的骨架片,考察了HPMC含量、HPMC粘度、甲硝唑粒度、片剂形状、片重、释放介质对药物释放的影响。
- Take two of the tablet three times daily before meals. 每日三次，每次两片，饭前服用。
- Fill a glass with water and dissolve this tablet in it. 倒杯水把药片放进去溶解了。
- Keywords Loxoprofen sodium;Mixed matrix tablet;Release velocity; 洛索洛芬钠;混合性缓释片;释药速率;
