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- Axon Guidance 1: Cues, Receptors, and Downstream Signalling Pathways Dickson, B. J. 轴突引导1:因子,接受器和下游信号传输。
- This article reviews the mechanisms, control genes and signalling pathways mediating cardiomyocyte apoptosis in myocardial ischemia/reperfusion injury. 现就心肌缺血/再灌注损伤中细胞凋亡发生的原因、参与调控的相关基因及信号途径作一综述。
- Errors in the way the bodys cells process information by means of signalling pathways are responsible for many diseases such as cancer, autoimmunity and diabetes. 多种不同的疾病,包括癌症、自体免疫疾病、糖尿病等等的出现,是由于人体细胞在处理不同的信号转导通路发生偏差。
- Glycogen synthase kinase 3 (GSK3) is a multifunctional serine/threonine kinase that participates in numerous signalling pathways involved in diverse physiological processes. 糖原合成酶激酶-3(GSK3)一个多功能的丝氨酸/苏氨酸激酶,参与多种生理过程涉及的很多信号通路。
- These effects are typically downstream consequences of suppression of cellular signalling pathways important in the regulation and maintenance of the microvasculature. 这些副作用主要是调节与维持微脉管系统中重要的细胞信号传导途径受到抑制、下调的结果。
- Finally, oxidants are involved in intracellular signalling pathways leading to activation of transcription factors and thus influencing gene transcription. 最后,氧化物通过干预细胞信号转导途径,导致转录因子的激活,而影响基因的转录。
- Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide. 活性氧通过信号通路介导心肌细胞肥大和凋亡;通过灭活一氧化氮等机制导致内皮功能紊乱。
- Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘着斑激酶(focal adhesion kinase,FAK)则是整合素信号途径中连接整合素与下级信号分子的媒介,是胞内多条信号途径的交汇点。
- OBJECTIVE : To explore various signal pathways and their correlation in the proliferation and differentiation of Schwann cells. 目的 :探讨许旺细胞增殖和分化过程中细胞内各种信号通路及其关联性。
- The important signal pathways included mitosis pathways, growth factor pathways, developing pathways and mucin pathways. 如:有丝分裂信号通路、生长因子信号通路、与发育有关的信号通路和黏蛋白信号通路。
- Many researches reveal that there are relations between cancers and aberrant activation or inactivation of signal pathways in cells. 现有研究揭示,许多癌症的发生与细胞内相关信号途径的异常激活或者失活相关。
- The aim of the present study was to investigate the possible signal pathways involved in the cardiovascular regulation of adenosine in the NTS. 本研究的目的在于研究孤束核中腺苷参与心血管调节的可能存在的信号通路。
- However, more research is necessary to do so.In this mini-review, we will focus on the potential signal pathways of BMPs in modulation the bone formation and regeneration. 在本篇回顾短文,我们将重点专注于骨形成蛋白参与骨形成过程所引发一连串的讯息作用途径,评估应用于骨或牙周组织再生之潜力。
- Following a brief introduction of relaxin family members, receptors and related signalling pathways, we review effects of relaxin on cardiovascular system, particularly, its anti-fibrotic action. 摘要简要介绍松弛素家族的成员、受体及其相关信号通路,重点回顾松弛素在心血管系统中的作用特别是其抗纤维化作用。
- Research indicated that PI3K and MAPK signal pathways were associated with biological behaviors such as cell migration, inflammation, cell proliferation and cell cycle regulation. 已有的研究表明PI3K和MAPK信号传导通路参与了细胞迁移、炎症反应、细胞增殖和细胞周期调控等一系列过程,在肾组织纤维化的发生发展中发挥重要作用。
- Several hypotheses have been advanced that link physical forces to intracellular signalling pathways, but in many cases the molecular mechanisms of mechanotransduction remain elusive. 已经提出了几个假说来连接物理力和细胞内信号转导通路但是许多情况中机械转导的机制还不清楚。
- Zhang -J et al.PDGF induces osteoprotegerin expression in vascular smooth muscle cells by multiple signal pathways[J]. FEBS-Lett.,2002 Jun 19;521(1-3):180-4. 廖二元等.;雌二醇对成骨细胞护骨素基因表达的影响[J]
- Method: The expression of DDR and its downstream signaling pathways were detected by IHC, WB, RT-PCR and FQ-PCR. 方法:以瘢痕疙瘩组织和KFb为对象,应用IHC、FQ-PCR,WB、RT-PCR研究DDR在瘢痕疙瘩中的表达;
- Signaling pathways downstream of pattern-recognition receptors and their cross talk. 信号通路下游的模式识别受体及其相互干扰作用。
- The two-component system may also act as a module linking cytokinin and other signaling pathways. 细胞分裂素与其它信号途径的互作可能也主要是通过双元组分系统链接的。