Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.

• 活性氧通过信号通路介导心肌细胞肥大和凋亡;通过灭活一氧化氮等机制导致内皮功能紊乱。